Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Wounds. 2023 Jan;35(1):E69-E73. doi: 10.25270/wnds/22055.
Delayed and incomplete healing of the skin graft at the donor site of an LD flap is common because of seroma formation. The authors aimed to evaluate whether the application of an NPD could improve the healing process after STSG at LD donor sites.
From July 2019 to September 2021, 32 patients underwent STSG with NPD at the LD donor site, and 27 patients underwent STSG with TBDs. Data were collected and analyzed using the chi-square test, t test, and Spearman correlation test.
The overall Spearman correlations of graft loss with seroma, hematoma, and infection were 0.56 (P <.01), 0.64 (P <.01), and 0.70 (P <.01), respectively. Compared with the TBD group, the STSG take rate was significantly higher in the NPD group (90.3% vs 84.5%, P =.046) while the seroma rate (18.8% vs 44.4%, P =.033), graft loss (9.4% vs 29.6%, P =.047), and mean length of stay (10.9 ± 1.8 vs 12.1 ± 2.4, P =.037) were significantly lower.
NPDs for STSG at the LD donor site contribute significantly to improved graft acceptance with reduced seroma formation.
由于血清肿的形成,皮瓣供区皮肤移植物的延迟和不完全愈合是很常见的。作者旨在评估 NPD 的应用是否能改善 LD 供区皮肤移植后的愈合过程。
2019 年 7 月至 2021 年 9 月,32 例患者在 LD 供区接受 NPD 下的 STSG,27 例患者在 TBD 下接受 STSG。使用卡方检验、t 检验和斯皮尔曼相关检验对数据进行收集和分析。
移植物丢失与血清肿、血肿和感染的总体斯皮尔曼相关系数分别为 0.56(P <.01)、0.64(P <.01)和 0.70(P <.01)。与 TBD 组相比,NPD 组 STSG 成活率显著更高(90.3%比 84.5%,P =.046),而血清肿发生率(18.8%比 44.4%,P =.033)、移植物丢失率(9.4%比 29.6%,P =.047)和平均住院时间(10.9 ± 1.8 比 12.1 ± 2.4,P =.037)均显著降低。
NPD 用于 LD 供区的 STSG 显著有助于改善移植物接受率,减少血清肿形成。