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内膜切除术和顺行性移植物治疗慢性内脏缺血的耐久性。

Durability of endarterectomy and antegrade grafts in the treatment of chronic visceral ischemia.

作者信息

Rapp J H, Reilly L M, Qvarfordt P G, Goldstone J, Ehrenfeld W K, Stoney R J

出版信息

J Vasc Surg. 1986 May;3(5):799-806. doi: 10.1067/mva.1986.avs0030799.

Abstract

Several techniques have been used to revascularize the visceral circulation. Although initially successful, these repairs often have a significant rate of late occlusion. To determine the durability of transaortic endarterectomy (TEA) and antegrade aortovisceral grafting, we reviewed the last 67 consecutive patients operated on at the University of California, San Francisco for chronic visceral ischemia. The patients were principally middle-aged (mean, 59 years) women (76%) with atherosclerotic disease involving at least two major visceral arteries. Forty-seven patients underwent TEA; 22 patients had associated renal endarterectomy, and 15 patients had simultaneous aortic reconstructions. Twenty patients had an aortovisceral antegrade bypass placed as their only reconstruction. Two of these had concomitant aortic reconstructions. There were five perioperative deaths. Of the 62 patients available for follow-up, 60 patients who had a total of 111 major visceral branch repairs have been followed up for 6 months to 14 years (mean, 4.4 years). Four patients (7%) have had recurrent visceral ischemia. Two patients had recurrent symptoms and have been asymptomatic for nearly 5 and 6 years, respectively, after successful reoperations. Two patients had intestinal infarction and died as a result. Thirty-four patients have had follow-up aortography that showed 58 widely patent reconstructions, two asymptomatic single-vessel stenoses, and one asymptomatic occlusion. TEA and antegrade visceral bypass provided long-term relief of symptoms and prevented visceral gangrene in 56 of 60 patients (93%). The prolonged patency of these reconstructions is attributed to the following: They originate from undiseased or endarterectomized aorta, they provide optimal, nonturbulent flow, and they avoid the inherent technical pitfalls of retrograde grafting.

摘要

已经采用了多种技术来重建内脏循环。尽管这些修复最初是成功的,但后期闭塞率往往很高。为了确定经主动脉内膜切除术(TEA)和顺行性主动脉内脏血管移植术的耐久性,我们回顾了加利福尼亚大学旧金山分校最近连续接受手术治疗慢性内脏缺血的67例患者。患者主要为中年(平均59岁)女性(76%),患有累及至少两条主要内脏动脉的动脉粥样硬化疾病。47例患者接受了TEA;22例患者同时进行了肾动脉内膜切除术,15例患者同时进行了主动脉重建。20例患者接受了顺行性主动脉内脏旁路移植术作为唯一的重建手术。其中2例同时进行了主动脉重建。围手术期死亡5例。在62例可供随访的患者中,60例共进行了111次主要内脏分支修复,随访时间为6个月至14年(平均4.4年)。4例患者(7%)出现复发性内脏缺血。2例患者出现复发症状,分别在成功再次手术后近5年和6年无症状。2例患者发生肠梗死并因此死亡。34例患者接受了随访主动脉造影,结果显示58处重建血管通畅,2处无症状单支血管狭窄,1处无症状闭塞。TEA和顺行性内脏旁路移植术使60例患者中的56例(93%)症状得到长期缓解,并预防了内脏坏疽。这些重建血管的长期通畅归因于以下几点:它们起源于未患病或已行内膜切除术的主动脉,提供了最佳的、无湍流的血流,并且避免了逆行移植固有的技术缺陷。

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