Chen Xinlong, Gan Yanling, Liu Dianchang
Department of Dermatology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 610072, People's Republic of China.
Department of STI and Leprosy Prevention and Control, Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, 250022, People's Republic of China.
Clin Cosmet Investig Dermatol. 2023 Mar 31;16:783-791. doi: 10.2147/CCID.S402676. eCollection 2023.
Gonorrhea, caused by the bacterium (NG), is a major public health concern worldwide.
The aim of this study is to understand the availability of laboratory diagnosis of gonorrhoea in Shandong province and its meaning in case reporting.
Two surveys were conducted among hospitals providing clinical services for sexually transmitted infection (STI) in Shandong Province in 2012 and 2018. The availability of laboratory tests for and distribution of reported gonorrhea cases were compared among different hospitals provided clinical services for STI in Shandong province. Descriptive analysis and Chi-square were used for statistical analysis.
Smear, culture and PCR tests for NG were used among 301(74.69%), 123(30.52%), 43(10.67%) hospitals in 2012 and 356(74.48%), 176(36.82%) and 73(15.27%) hospitals in 2018, respectively. Significant differences were observed in the availability of smear among hospitals at different levels (X=12.159, p=0.000) and with different affiliations (X=4.551, p=0.033) in 2018. Significant differences were observed in the availability of culture and PCR tests among hospitals at different levels both in 2012 (X=34.532, p=0.000; X=7.380, p=0.007) and 2018 (X=49.820, p=0.000; X=21.658, p=0.000). The availability of culture and PCR tests for NG among hospitals in 2018 was higher than that in 2012 (X=3.870, p=0.049; X=4.050, p=0.044). More hospitals reported gonorrhea cases in 2018 than in 2012 (X=6.768, p=0.009). A significant difference was observed in distribution of case reporting among hospitals at different levels in 2018 (X=6.975, p=0.008) and among different types of hospital both in 2012 (X=52.362, p=0.000) and 2018 (X=74.478, p=0.000).
Poor availability of NG laboratory tests affects case reporting, and which is a crucial reason leading to underreporting of gonorrhea cases in Shandong province.
由淋病奈瑟菌（NG）引起的淋病是全球主要的公共卫生问题。
本研究旨在了解山东省淋病实验室诊断的可及性及其在病例报告中的意义。
2012年和2018年对山东省提供性传播感染（STI）临床服务的医院进行了两次调查。比较了山东省不同提供STI临床服务的医院中NG实验室检测的可及性以及报告淋病病例的分布情况。采用描述性分析和卡方检验进行统计分析。
2012年，301家（74.69%）、123家（30.52%）、43家（10.67%）医院分别采用了NG涂片、培养和PCR检测，2018年分别为356家（74.48%）、176家（36.82%）和73家（15.27%）医院。2018年，不同级别医院（X=12.159，p=0.000）和不同隶属关系医院（X=4.551，p=0.033）的涂片检测可及性存在显著差异。2012年（X=34.532，p=0.000；X=7.380，p=0.007）和2018年（X=49.820，p=0.000；X=21.658，p=0.000）不同级别医院的培养和PCR检测可及性均存在显著差异。2018年医院中NG培养和PCR检测的可及性高于2012年（X=3.870，p=0.049；X=4.050，p=0.044）。2018年报告淋病病例的医院比2012年多（X=6.768，p=0.009）。2018年不同级别医院（X=6.975，p=0.008）以及2012年（X=52.362，p=0.000）和2018年（X=74.478，p=0.000）不同类型医院的病例报告分布存在显著差异。
NG实验室检测可及性差影响病例报告，这是导致山东省淋病病例报告不足的关键原因。
