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[勘误] 大黄素通过Nrf2信号通路对U251细胞和APP/PS1小鼠阿尔茨海默病的神经保护作用

[Corrigendum] Neuroprotective effect of emodin against Alzheimer's disease via Nrf2 signaling in U251 cells and APP/PS1 mice.

作者信息

Li Zhiping, Bi Hui, Jiang Hongbo, Song Jingjing, Meng Qingfan, Zhang Yizhi, Fei Xiaofang

机构信息

Department of Pharmacy, The First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.

Department of Anesthesiology, Hospital of Stomatology, Jilin University, Changchun, Jilin 130021, P.R. China.

出版信息

Mol Med Rep. 2023 May;27(5). doi: 10.3892/mmr.2023.12994. Epub 2023 Apr 7.

DOI:10.3892/mmr.2023.12994
PMID:37026528
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10098031/
Abstract

Subsequently to the publication of this paper, an interested reader drew to the authors' attention that the lower left panel of Fig. 3A of this paper had already featured in the following paper, which featured one of the same authors (Zhiping Li): Zhang Y, Wang J, Wang C, Li Z, Liu X, Zhang J, Lu J and Wang D: Pharmacological basis for the use of evodiamine in Alzheimer's disease: antioxidation and antiapoptosis. Int J Mol Sci 21: 1527, 2018. Moreover, an independent analysis of the data in this paper conducted by the Editorial Office revealed that the Bcl‑2 protein western blotting data featured in Fig. 3C had apparently also appeared in a previous publication featuring the same author [Qiu Y, Jiang X, Liu D, Deng Z, Hu W, Li Z and Li Y: The hypoglycemic and renal protection properties of crocin via oxidative stress‑regulated NF‑κB signaling in db/db mice. Front Pharmacol 30: 541, 2020].  After having examined their original data, the authors have realized that Fig. 3 in the above paper had been inadvertently assembled incorrectly, owing to the mishandling of certain of the data. In addition, the authors wished to present a revised version of Fig. 4 containing more representative data for Fig. 4C and D. The corrected versions of Figs. 3 and 4, featuring the correct data for Fig. 3A and C, and the revised data in Fig. 4C and D, are shown on the next two pages. Note that these errors did not significantly affect the results or the conclusions reported in this paper, and all the authors agree to the publication of this Corrigendum. The authors are grateful to the Editor of for granting them the opportunity to publish this corrigendum, and apologize to the readership for any inconvenience caused. [Molecular Medicine Reports 23: 108, 2021; DOI: 10.3892/mmr.2020.11747].

摘要

在本文发表之后,一位感兴趣的读者提请作者注意,本文图3A的左下角图已在以下论文中出现过,该论文的作者之一与本文相同(李志平):Zhang Y, Wang J, Wang C, Li Z, Liu X, Zhang J, Lu J和Wang D:吴茱萸碱用于阿尔茨海默病的药理学基础:抗氧化和抗凋亡作用。《国际分子科学杂志》21: 1527, 2018。此外,编辑部对本文数据进行的独立分析显示,图3C中的Bcl-2蛋白western印迹数据显然也已出现在之前一篇有同一作者的出版物中[Qiu Y, Jiang X, Liu D, Deng Z, Hu W, Li Z和Li Y:藏红花素通过氧化应激调节的NF-κB信号通路对db/db小鼠的降血糖和肾脏保护作用。《药理学前沿》30: 541, 2020]。在检查了原始数据后,作者意识到上述论文中的图3由于某些数据处理不当而被无意中错误组装。此外,作者希望提供图4的修订版,其中包含图4C和D更具代表性的数据。图3和图4的校正版本,分别呈现了图3A和C的正确数据以及图4C和D的修订数据,见接下来的两页。请注意,这些错误并未显著影响本文所报道的结果或结论,所有作者均同意发表本勘误。作者感谢《分子医学报告》的编辑给予他们发表本勘误的机会,并就由此给读者带来 的不便表示歉意。[《分子医学报告》23: 108, 2021;DOI: 10.3892/mmr.2020.11747]

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c7f/10098031/2eef9d5fffee/mmr-27-05-12994-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c7f/10098031/105474aef430/mmr-27-05-12994-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c7f/10098031/2eef9d5fffee/mmr-27-05-12994-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c7f/10098031/105474aef430/mmr-27-05-12994-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c7f/10098031/2eef9d5fffee/mmr-27-05-12994-g01.jpg

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