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[Monitoring of heparinization in cardiac surgery with ACT: accreditation of the point-of-care test in the Bordeaux University Hospital Centre].

作者信息

Landrieu Valentin, Beauvieux Marie Christine, Vidal Thomas, Mouton Christine, Castaing-Mouhica Gladys, Dusseau Laurent, Stanciu Eugen, Domingorena Julien, Roux David, Catel Julien, Moreno Valerie, Berthon Nathalie, Bachellerie Delphine, Poisvert Sandy, Delassasseigne Céline

机构信息

Service d'Hématologie, CHU de Bordeaux, Hôpital Haut-Lévêque 33604 Pessac Cedex, France.

Service de Biochimie CHU de Bordeaux, et RMSB UMR 5536 CNRS -Université de Bordeaux, France.

出版信息

Ann Biol Clin (Paris). 2023 May 16;81(2):168-180. doi: 10.1684/abc.2023.1794.

Abstract

ACT (Activated Clotting Time) is a point of care test (POCT) on whole blood, used to monitor the heparinization of patients in the operating room in cardiac surgery (ExtraCorporeal Circulation ECC) and in interventional cardiology (TAVI, AF ablation). The ACT is concerned both by the ISO 22 870 standard and French regulations regarding POCT. We performed an important work at the Bordeaux CHU on its accreditation, by rationalizing and making the park uniform (11 HemochronTM Signature Elite), standardizing the training and the habilitation of operators in medical units, introducing periodic quality controls, centralizing in the laboratory the management of the devices and reagents and by connecting it to the laboratory's computer system (Middleware, SIL et expert softwares). One year after, we have some positive feedbacks with only a few technical problems and with only few remarks raised during internal audits.

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