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瑞士癌症患者临终关怀连续性和治疗强度。

Continuity of care and treatment intensity at the end of life in Swiss cancer patients.

机构信息

Department of Health Sciences, Helsana Group, Zürich, Switzerland.

Department of General Practice, Primary Care, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

出版信息

Eur J Public Health. 2023 Jun 1;33(3):396-402. doi: 10.1093/eurpub/ckad047.

DOI:10.1093/eurpub/ckad047
PMID:37029913
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10234661/
Abstract

BACKGROUND

Continuity of care (COC) was shown to be associated with fewer hospitalizations. We aimed to evaluate whether COC was associated with intensive intervention(s) at the end of life (IEOL), a preference-sensitive outcome, in cancer patients.

METHODS

The study is based on claims data of patients with incident use of anti-neoplastics in Switzerland. COC Index, Usual Provider Continuity score, Sequential Continuity index and Modified Modified Continuity Index were calculated based on consultations with the usual ambulatory care physician. Treatment intensity was evaluated in the last 6 months of life, and COC was evaluated in months 18-6 before death in those who died between 24 and 54 months after incident cancer. IEOL comprised life-sustaining interventions (cardiac catheterization, cardiac assistance device implantation, pulmonary artery wedge monitoring, cardiopulmonary resuscitation/cardiac conversion, gastrostomy, blood transfusion, dialysis, mechanical ventilator utilization and intravenous antibiotics) and measures specifically used in cancer patients (last dose of chemotherapy ≤14 days of death, a new chemotherapy regimen starting <30 days before death, ≥1 emergency visit in the last month of life, ≥1 hospital admission or spending >14 days in hospital in the last month of life and death in an acute-care hospital).

RESULTS

All COC scores were inversely associated with the occurrence of an IEOL, as were older age, homecare nursing utilization and density of ambulatory care physicians. For COC Index, odds ratio was 0.55 (95% confidence interval 0.37-0.83).

CONCLUSIONS

COC scores were consistently and inversely related to IEOL. The study supports efforts to improve COC for cancer patients at their end of life.

摘要

背景

连续性护理(COC)与减少住院治疗相关。我们旨在评估 COC 是否与癌症患者生命末期(IEOL)的强化干预(s)相关,这是一个偏好敏感的结果。

方法

该研究基于瑞士接受抗肿瘤药物治疗的患者的索赔数据。COC 指数、常规提供者连续性评分、连续顺序指数和改良连续指数是根据与常规门诊医生的就诊计算得出的。在生命的最后 6 个月评估治疗强度,并在癌症发病后 24 至 54 个月内死亡的患者中,在死亡前 18-6 个月评估 COC。IEOL 包括生命维持干预(心导管检查、心脏辅助设备植入、肺动脉楔压监测、心肺复苏/心脏转换、胃造口术、输血、透析、机械通气利用和静脉内抗生素)和专门用于癌症患者的措施(死亡前 14 天内最后一次化疗剂量、死亡前 30 天内开始新的化疗方案、生命最后一个月内至少 1 次急诊就诊、生命最后一个月内至少 1 次住院或住院 14 天以上、急性护理医院死亡)。

结果

所有 COC 评分均与 IEOL 的发生呈负相关,年龄较大、家庭护理利用和门诊医生密度也是如此。对于 COC 指数,比值比为 0.55(95%置信区间为 0.37-0.83)。

结论

COC 评分与 IEOL 呈一致的负相关。该研究支持努力改善癌症患者生命末期的 COC。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/094b/10234661/c8b3ac234677/ckad047f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/094b/10234661/c8b3ac234677/ckad047f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/094b/10234661/c8b3ac234677/ckad047f1.jpg

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JAMA Health Forum. 2022 Jan 4;3(1):e214464. doi: 10.1001/jamahealthforum.2021.4464.
2
Palliative Care and Life-Sustaining/Local Procedures in Colorectal Cancer in the United States Hospitals: A Ten-Year Perspective.美国医院结直肠癌的姑息治疗与维持生命/局部治疗:十年视角
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Care of the adult cancer patient at the end of life: ESMO Clinical Practice Guidelines.
成人癌症终末期患者的护理:ESMO 临床实践指南。
ESMO Open. 2021 Aug;6(4):100225. doi: 10.1016/j.esmoop.2021.100225. Epub 2021 Aug 17.
4
Primary care physician continuity, survival, and end-of-life care intensity.初级保健医生的连续性、生存率及临终关怀强度。
Health Serv Res. 2022 Aug;57(4):853-862. doi: 10.1111/1475-6773.13869. Epub 2021 Sep 6.
5
Continuity of Care in Swiss Cancer Patients Using Claims Data.利用索赔数据研究瑞士癌症患者的连续护理情况。
Patient Prefer Adherence. 2020 Nov 18;14:2253-2262. doi: 10.2147/PPA.S266381. eCollection 2020.
6
Better continuity of care improves the quality of end-of-life care among elderly patients with end-stage renal disease.更好的医疗连续性可提高终末期肾病老年患者的临终关怀质量。
Sci Rep. 2020 Nov 12;10(1):19716. doi: 10.1038/s41598-020-76707-w.
7
An early palliative care intervention can be confronting but reassuring: A qualitative study on the experiences of patients with advanced cancer.早期姑息治疗干预可能具有挑战性,但也能让人安心:一项关于晚期癌症患者体验的定性研究。
Palliat Med. 2019 Jul;33(7):783-792. doi: 10.1177/0269216319847884. Epub 2019 May 9.
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