Servicio de Farmacia, Hospital Santa Creu i Sant Pau, Barcelona, Spain.
Int J Pharm Pract. 2023 Jun 30;31(4):417-422. doi: 10.1093/ijpp/riad022.
Drug-related problems (DRPs) are a well-known cause of emergency department (ED) visits. The objective of the FARM-URG project was to assess the prevalence of DRPs using an annual cross-sectional registry. Herein we report results of the first 3 years, indicating the prevalence of DRPs, drugs involved, and patient characteristics.
A point-prevalence multicenter study was conducted across EDs of hospitals in Spain. A specified day and hour was assigned to collect data from all adult patients attending the ED due to DRPs during three consecutive years. Medical records were retrospectively reviewed, with data recorded in REDCap.
Overall, 4752 patients were evaluated at 32 centres, of which 366 (7.7%) visited the ED due to DRPs, with a prevalence ranging from 0 to 16.7%. Antithrombotic drugs accounted for the highest number of DRPs, responsible for 96 (26.8%) episodes. Falls (n = 29; 8.0%) were the most frequent DRPs, followed by haemorrhage (n = 26; 7.12%). Furthermore, 198 (54.2%) reported DRPs were unrelated to medication errors, 80 (21.2%) were overdose errors, and 40 (11.0%) were attributed to poor treatment adherence. Of 366 DRPs-related visits, 54 (14.8%) were due to inappropriately prescribed drugs according to the STOPP-START criteria. Overall, 86 (23.5%) patients revisited the ED within 30 days of discharge, with 34 (9.4%) returning to the ED for new DRPs.
DRPs are frequently responsible for ED visits and are associated with a considerable percentage of post-discharge visits. The goal of the FARM-URG project is to periodically gather data to design and implement preventive measures.
药物相关问题（DRP）是急诊科（ED）就诊的一个已知原因。FARM-URG 项目的目的是使用年度横断面登记来评估 DRP 的患病率。在此，我们报告了前 3 年的结果，表明了 DRP 的患病率、涉及的药物和患者特征。
在西班牙医院的 ED 进行了一项点患病率多中心研究。指定了一天中的一个特定时间，以便在连续三年中收集因 DRP 而就诊 ED 的所有成年患者的数据。对医疗记录进行回顾性审查，并在 REDCap 中记录数据。
总体而言，在 32 个中心评估了 4752 名患者，其中 366 名（7.7%）因 DRP 就诊 ED，患病率从 0 到 16.7%不等。抗血栓药物导致的 DRP 数量最多，占 96 例（26.8%）。跌倒（n=29；8.0%）是最常见的 DRP，其次是出血（n=26；7.12%）。此外，198 例（54.2%）报告的 DRP 与药物错误无关，80 例（21.2%）是用药过量错误，40 例（11.0%）是由于治疗依从性差。在 366 例与 DRP 相关的就诊中，根据 STOPP-START 标准，54 例（14.8%）因药物使用不当而就诊。总体而言，86 例（23.5%）患者在出院后 30 天内再次就诊 ED，其中 34 例（9.4%）因新的 DRP 再次就诊 ED。
DRP 经常是 ED 就诊的原因，并与相当大比例的出院后就诊有关。FARM-URG 项目的目标是定期收集数据，以设计和实施预防措施。
