Department of Thoracic Oncology, King Hussein Cancer Center, Amman, Jordan.
Department of Research, King Hussein Cancer Center, Queen Rania Al Abdullah Street, Amman, 11941, Jordan.
J Cardiothorac Surg. 2023 Apr 8;18(1):114. doi: 10.1186/s13019-023-02213-5.
Primary sternal chondrosarcoma, although rare, is the most common malignant tumor of the sternum. The gold standard treatment is complete surgical excision, which frequently causes the instability of the thorax necessitating future reconstruction. Local recurrence is common increasing the risk of distant metastasis.
A 60-year-old male patient was diagnosed with primary sternum chondrosarcoma and underwent surgical excision with negative resection margins. Later, he was found to have two local recurrences at 11 months and 37 months post initial excision. The two recurrences were surgically removed followed by local adjuvant radiation.
The seeding theories have been reported more frequently with relation to diagnostic biopsy procedures, tumor manipulation and self-seeding tumors. The patient developed two local recurrences despite total resection with negative margins, without concerns regarding seeding in distant metastasis.
原发性胸骨软骨肉瘤虽然罕见，但却是胸骨最常见的恶性肿瘤。金标准治疗方法是完全手术切除，这经常导致胸腔不稳定，需要未来进行重建。局部复发很常见，增加了远处转移的风险。
一名 60 岁男性患者被诊断为原发性胸骨软骨肉瘤，并接受了手术切除，切缘阴性。之后，他在初次切除后 11 个月和 37 个月时发现了两处局部复发。这两次复发均通过手术切除，并进行了局部辅助放疗。
播种理论更多地与诊断性活检、肿瘤操作和自播种肿瘤有关。尽管患者进行了完全切除且切缘阴性，但仍出现了两处局部复发，而无远处转移的播种担忧。
