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恶性颅内孤立性纤维瘤:一例报告及文献复习

Malignant intracranial solitary fibrous tumor: A case report and literature review.

作者信息

Nhung Ta Hong, Minh Vu Le, Lam Ngo-Le, Lien Nguyen Duc, Duc Nguyen Minh

机构信息

Department of Radiology, Vietnam National Cancer Hospital, 2 Duong Quang Trung, Ward 12, District 10, Hanoi, Vietnam.

Department of Neurosurgery, Vietnam National Cancer Hospital, Hanoi, Vietnam.

出版信息

Radiol Case Rep. 2023 Mar 23;18(5):2014-2018. doi: 10.1016/j.radcr.2023.02.064. eCollection 2023 May.

Abstract

Solitary fibrous tumor (SFT), previously termed hemangiopericytoma, is a rare primary intracranial tumor. SFT is classified into grades I, II, and III with different prognoses; grade III tumor has malignant characteristics with a high probability of recurrence and extracranial metastasis. We report the case of a 63-year-old female patient admitted to the Vietnam National Cancer Hospital with headache, dizziness, nausea, ataxia, and loss of balance. Computed tomography showed a markedly enhanced tumor, without calcification, located in the posterior fossa close to the tentorium cerebelli. No changes in the adjacent bone were seen. Magnetic resonance imaging revealed a lobular extra-axial tumor with prominent flow voids, a finding that has been seen frequently in these tumors. The tumor was resected following an initial diagnosis of SFT. Postoperative histology indicated a grade III SFT according to the World Health Organization 2021 classification. SFT is often misdiagnosed as meningioma, as they have some imaging features in common. However, we believe that there are some characteristic magnetic resonance imaging features that help to distinguish between these tumors, as well as playing an essential role in SFT grading and potentially guiding the best therapeutic decision.

摘要

孤立性纤维瘤(SFT),以前称为血管外皮细胞瘤,是一种罕见的原发性颅内肿瘤。SFT分为I级、II级和III级,预后不同;III级肿瘤具有恶性特征,复发和颅外转移的可能性很高。我们报告了一名63岁女性患者的病例,该患者因头痛、头晕、恶心、共济失调和平衡失调入住越南国家癌症医院。计算机断层扫描显示一个明显强化的肿瘤,无钙化,位于后颅窝靠近小脑幕处。未见相邻骨质改变。磁共振成像显示一个具有明显流空信号的小叶状轴外肿瘤,这一表现常见于这些肿瘤。在初步诊断为SFT后,该肿瘤被切除。术后组织学检查根据世界卫生组织2021年分类显示为III级SFT。SFT常被误诊为脑膜瘤,因为它们有一些共同的影像学特征。然而,我们认为有一些特征性的磁共振成像特征有助于区分这些肿瘤,并且在SFT分级中起着重要作用,并可能指导最佳治疗决策。

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