Hou Min, Duan Xiao-Jing, An Yan, You Ji-Peng, Bi Liang-Liang, Zhou Xuan, Wan Jie, Qu Yi
Department of Ultrasonography, Affiliated Hospital of Hebei University, Baoding, China.
Department of Obstetrics, Affiliated Hospital of Hebei University, Baoding, China.
Front Cardiovasc Med. 2023 Mar 23;10:920965. doi: 10.3389/fcvm.2023.920965. eCollection 2023.
The aim of this study was to evaluate the left and right ventricular segmental and global myocardial function of normal fetuses using velocity vector imaging and explore the correlation between global myocardial function parameters and gestational age.
A total of 127 normal fetuses were selected and divided into five groups according to gestational age for the measurement of their left and right ventricular segmental and global velocity, strain, and strain rate. This study also explored the change trend in the global myocardial function parameters at different gestational ages and analyzed its correlation with gestational age.
The peak velocities of the biventricular segments of the normal fetuses showed a decreasing trend from the basal to the middle to the apex segment, and the differences were statistically significant ( < 0.05). However, the strain and peak strain rate between adjacent segments showed no significant differences ( > 0.05). The peak global velocity of both ventricles increased with the gestational age, and it was moderately correlated with gestational age; however, the correlation of strain and peak strain rate with gestational age was not statistically significant ( > 0.05).
In normal fetuses, the peak myocardial velocity of the biventricular segments showed a decreasing trend from the basal to the apical segment. The global peak myocardial velocity was linearly correlated with gestational age; however, the global strain and peak strain rate did not change as gestational age increased, indicating that the myocardial deformability of the fetus' ventricles was constant in the middle and late trimesters.
本研究旨在利用速度向量成像评估正常胎儿左右心室节段性和整体心肌功能，并探讨整体心肌功能参数与胎龄之间的相关性。
选取127例正常胎儿，根据胎龄分为五组，测量其左右心室节段性和整体的速度、应变及应变率。本研究还探讨了不同胎龄时整体心肌功能参数的变化趋势，并分析其与胎龄的相关性。
正常胎儿双心室各节段的峰值速度从心底段到中间段再到心尖段呈递减趋势，差异有统计学意义（<0.05）。然而，相邻节段之间的应变及峰值应变率差异无统计学意义（>0.05）。双心室的整体峰值速度随胎龄增加而升高，且与胎龄呈中度相关；但应变及峰值应变率与胎龄的相关性无统计学意义（>0.05）。
在正常胎儿中，双心室节段的心肌峰值速度从心底段到心尖段呈递减趋势。整体心肌峰值速度与胎龄呈线性相关；然而，整体应变及峰值应变率并不随胎龄增加而变化，这表明胎儿心室的心肌变形能力在孕中晚期是恒定的。
