Vinh Quang Bui, Quoc Soai Dang, Van Toan Hoang, Vu Truong, Thi Tuyet Pham
Radiotherapy Department, Hanoi Oncology Hospital, Hai Ba Trung, Hanoi 100000, Vietnam.
Medical Physics Division, Hanoi Oncology Hospital, Hai Ba Trung, Hanoi 100000, Vietnam.
Mol Clin Oncol. 2023 Mar 30;18(5):43. doi: 10.3892/mco.2023.2639. eCollection 2023 May.
In the present study, it was aimed to investigate the optimized plan of radiotherapy with dose modulation in the pelvis to reduce the dose on the skin in patients having pelvic region radiotherapy. The series of images of 45 pelvic cancer patients were selected, intensity-modulated radiation therapy (IMRT) plan was made, the skin dose reduction was optimized, and evaluated verifying the plan verification. As a result, skin volume receiving dose ≥10, ≥20, ≥30, ≥40 and ≥50 Gy of the IMRT Skin plan were all less than those of the IMRT plan. Particularly, skin volumes receiving doses ≥20, ≥30, ≥40 and ≥50 Gy of the Skin IMRT plan were markedly lower than those of the IMRT plan, the reduction values were 8.76, 18.83, 46.84 and 100%, respectively. Furthermore, the Skin IMRT plan was no longer affected by the 50 Gy dose. In conclusion, the present study revealed that the skin's dose can be decreased with optimal plan processing; thus, this decrease of the skin's dose ensures the continuation of radiotherapy and improved life quality of the patient.
在本研究中，旨在探讨盆腔放疗中剂量调制的优化放疗计划，以减少盆腔区域放疗患者皮肤的剂量。选取了45例盆腔癌患者的系列图像，制定调强放射治疗（IMRT）计划，优化皮肤剂量降低，并通过计划验证进行评估。结果显示，IMRT皮肤计划中接受剂量≥10、≥20、≥30、≥40和≥50 Gy的皮肤体积均小于IMRT计划。特别是，皮肤IMRT计划中接受剂量≥20、≥30、≥40和≥50 Gy的皮肤体积明显低于IMRT计划，降低值分别为8.76%、18.83%、46.84%和100%。此外，皮肤IMRT计划不再受50 Gy剂量的影响。总之，本研究表明，通过优化计划处理可以降低皮肤剂量；因此，皮肤剂量的降低确保了放疗的持续进行并提高了患者的生活质量。
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