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评价替来他明-唑拉西泮、美托咪定和阿扎哌隆联合鼻腔给氧在巴拉圭查科地区固定饲养的查科羊驼(Catagonus wagneri)中的应用。

EVALUATION OF A COMBINATION OF TILETAMINE-ZOLAZEPAM, MEDETOMIDINE, AND AZAPERONE WITH NASAL OXYGEN SUPPLEMENTATION FOR THE IMMOBILIZATION OF CAPTIVE CHACOAN PECCARIES (CATAGONUS WAGNERI) IN THE CHACO REGION OF PARAGUAY.

机构信息

Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, 2015 SW 16th Avenue, Gainesville, Florida 32610, USA.

Department of Wildlife, Ecology and Conservation, University of Florida, Institute of Food and Agricultural Sciences, 110 Newins-Ziegler Hall, Gainesville, Florida 32611, USA.

出版信息

J Wildl Dis. 2023 Apr 1;59(2):281-287. doi: 10.7589/JWD-D-21-00203.

Abstract

A combination of tiletamine-zolazepam, medetomidine, and azaperone was used to immobilize captive Chacoan peccaries (Catagonus wagneri) for health assessments and biological sample collection at the Centro Chaqueño para la Conservación e Investigación (CCCI) in the Paraguayan Chaco during July in 2017 and 2018. In total, 83 peccaries kept in 0.25-1.50 hectare enclosures were immobilized via dart-administered anesthetic. Mean animal weight was 33.89±3.74 kg (standard deviation; n=77). The mean intramuscular (IM) anesthetic drug and dosages were 0.03±0.00 mg/kg of medetomidine, 0.91±0.10 mg/kg of Zoletil 50 (tiletamine-zolazepam), and 0.30±0.03 mg/kg azaperone. The mean time to recumbency after darting was 6.07±2.65 min. The mean time to reach the anesthetic plane postdarting was 10.00±2.00 min. Muscle relaxation was adequate to allow minor veterinary procedures. A mean dosage of 0.15±0.02 mg/kg of atipamezole was given IM to reverse the medetomidine. Recoveries were smooth and animals were standing by 59.17±30.18 min postreversal. Full recovery and release back to enclosures occurred 90±30 min postreversal. A single dose of this drug combination provided adequate anesthesia for 88% of adult Chacoan peccaries; 12% needed a supplemental dose of tiletamine-zolazepam because of failure to receive the full dose from the anesthetic dart. Sex and age did not impact the dosage required to achieve immobilization. Confinement during recovery from anesthesia is required with this protocol. Aside from mild hypoxemia, no adverse effects from anesthesia were observed. However, oxygen supplementation as a part of this protocol is recommended to support circulatory and respiratory capacity.

摘要

替来他明-唑拉西泮、甲磺酸达托咪定和唑吡坦联合用于 2017 年和 2018 年 7 月在巴拉圭查科的 Centro Chaqueño para la Conservación e Investigación(CCCI)对圈养的查科野猪(Catagonus wagneri)进行健康评估和生物样本采集。总共对 83 头圈养在 0.25-1.50 公顷围栏中的野猪进行了通过镖枪给药的麻醉。平均动物体重为 33.89±3.74kg(标准差;n=77)。肌肉内(IM)麻醉药物的平均剂量为:0.03±0.00mg/kg 甲磺酸达托咪定、0.91±0.10mg/kg Zoletil 50(替来他明-唑拉西泮)和 0.30±0.03mg/kg 唑吡坦。镖枪后卧床时间平均为 6.07±2.65min。镖枪后达到麻醉平面的平均时间为 10.00±2.00min。肌肉松弛足以进行小型兽医程序。IM 给予平均剂量 0.15±0.02mg/kg 阿替美唑逆转甲磺酸达托咪定的作用。恢复平稳,动物在逆转后 59.17±30.18min 后站立。逆转后 90±30min 完全恢复并释放回围栏。这种药物组合的单次剂量为 88%的成年查科野猪提供了足够的麻醉;12%的动物由于未能从麻醉镖枪中获得全剂量,需要补充替来他明-唑拉西泮剂量。性别和年龄不影响达到麻醉所需的剂量。在从麻醉中恢复期间需要限制动物活动。除了轻度低氧血症外,没有观察到麻醉的不良反应。但是,建议将氧补充作为该方案的一部分,以支持循环和呼吸能力。

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