Jeong Dong-Hyuk, Yang Jeong-Jin, Seok Seong-Hoon, Song Byeung-Cheul, Yeon Seong-Chan
1 Species Restoration Technology Institute, Korea National Park Service, Hwaeomsaro 402-31, Gurye 57616, Republic of Korea.
2 Laboratory of Veterinary Surgery and Behavior, College of Veterinary Medicine, Gyeongsang National University, Jinjudaero 501, Jinju 52828, Republic of Korea.
J Wildl Dis. 2017 Jul;53(3):636-641. doi: 10.7589/2016-05-118. Epub 2017 Mar 21.
The Asiatic black bear ( Ursus thibetanus ; ABB) is a globally endangered species for which a restoration program has been ongoing in South Korea since 2001. However, there is little information on immobilization protocols for ABBs. We evaluated the use of medetomidine-zolazepam-tiletamine for their immobilization. During 2005-13, we anesthetized 60 ABBs (32 males, 28 females; 7 mo to 12 yr old) with medetomidine 0.03-0.045 mg/kg and zolazepam-tiletamine 1.54-2.3 mg/kg; reversal of anesthesia was done with atipamezole 0.15-0.225 mg/kg administered intravenously alone or intravenously and intramuscularly (50:50). Mean (and SD) for physiologic collected for 373 immobilizations of at least 60 min were: time to sedation, 7.8 (5.4) min; anesthesia induction time, 13.7 (8.1) min; complete recovery time, 14.8 (12.4) min; respiratory rate, 14 (7) breaths/min; heart rate, 51 (16) beats/min; rectal temperature, 37.3 (1.3) C; and hemoglobin oxygen saturation, 88% (6%). Few cardiopulmonary side effects occurred during immobilization and adequate depth of anesthesia was maintained for >60 min without need for supplementation. The dosage and drug combination used was effective for immobilization of ABBs with minimal adverse effects on vital signs and can be recommended in most clinical applications.
亚洲黑熊(Ursus thibetanus;ABB)是一种全球濒危物种,自2001年以来韩国一直在开展针对该物种的恢复计划。然而,关于亚洲黑熊的麻醉方案的信息却很少。我们评估了美托咪定-唑拉西泮-替来他明用于麻醉亚洲黑熊的效果。在2005年至2013年期间,我们用0.03 - 0.045毫克/千克的美托咪定和1.54 - 2.3毫克/千克的唑拉西泮-替来他明麻醉了60只亚洲黑熊(32只雄性,28只雌性;年龄在7个月至12岁之间);单独静脉注射或静脉注射与肌肉注射(50:50)0.15 - 0.225毫克/千克的阿替美唑进行麻醉苏醒。对至少60分钟的373次麻醉过程中收集的生理数据的平均值(及标准差)如下:镇静时间,7.8(5.4)分钟;麻醉诱导时间,13.7(8.1)分钟;完全恢复时间,14.8(12.4)分钟;呼吸频率,14(7)次/分钟;心率,51(16)次/分钟;直肠温度,37.3(1.3)摄氏度;血红蛋白氧饱和度,88%(6%)。麻醉过程中很少出现心肺副作用,并且在无需补充麻醉剂的情况下,麻醉深度维持超过60分钟。所使用的剂量和药物组合对亚洲黑熊的麻醉有效,对生命体征的不良影响最小,可推荐用于大多数临床应用。