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国家心脏病学研究所冠状动脉扩张的展望:一项横断面研究。

Outlook of coronary ectasia at the National Institute of Cardiology Ignacio Chávez: a cross-sectional study.

机构信息

Servicio de Hospitalización, Departamento de Cardiología Adultos, Instituto Nacional de Cardiología Ignacio Chávez.

Escuela Superior de Medicina, Instituto Politécnico Nacional.

出版信息

Arch Cardiol Mex. 2023;93(2):197-202. doi: 10.24875/ACM.21000380.

DOI:10.24875/ACM.21000380
PMID:37037216
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10161814/
Abstract

INTRODUCTION

Coronary Ectasia (CE) is a pathological remodeling with a low worldwide prevalence. It is defined as a diffuse dilatation greater than 1.5 times the diameter of the adjacent segments of the same or different coronary arteries.

OBJECTIVE

To document the clinical and angiographic characteristics, and medical treatment at the discharge of patients diagnosed with coronary ectasia who attended the National Institute of Cardiology (INC).

METHODS

Cross-sectional study with a non-experimental descriptive design, with a non-probabilistic convenience sampling.

RESULTS

Of 69 patients who attended the INC with a diagnosis of CD, most were men, with a mean age of 56 + 11 years, the most common coronary risk factor in patients with CE was smoking 58% (40); it was associated mostly with an acute myocardial infarction ST-segment elevation (STEMI) 65.2% (45), of frequent location in the lower face 40% (18), correlated with the most affected artery is the Right Coronary Artery (CD) 69.6% (48), followed by the circumflex (Cx) 56.5% (39). A mean LVEF of 47 + 9.72 was evident within the ventricular function. As well as the preferential use of dual antiplatelet therapy with anticoagulant (DAP + OAC) in 58% (40) at the discharge of each patient from the INC.

CONCLUSION

CE is a not uncommon pathological remodeling in INC. This study showed that STEMI is the most typical manifestation of CE, diagnostic coronary angiography identified a type 3 Markis, so a low rate of mortality and recurrence of cardiovascular events would be expected, and despite the lack of consensus on the ideal therapy, at the INC individualized treatment is preferred, recommending lifestyle changes, and using triple therapy (DAP + OAC) as a medical treatment only at the time of patient discharge.

摘要

介绍

冠状动脉扩张症(CE)是一种全球发病率较低的病理性重塑。它被定义为同一或不同冠状动脉的相邻节段直径扩张超过 1.5 倍。

目的

记录在国家心脏病研究所(INC)就诊的被诊断为冠状动脉扩张症患者的临床和血管造影特征以及出院时的治疗情况。

方法

采用非实验性描述性设计的横断面研究,采用非概率便利抽样。

结果

在 INC 就诊并被诊断为 CD 的 69 名患者中,大多数为男性,平均年龄为 56+11 岁,CE 患者最常见的冠状动脉风险因素是吸烟,占 58%(40 例);CE 主要与急性心肌梗死 ST 段抬高(STEMI)相关,占 65.2%(45 例),常见部位在下壁,占 40%(18 例),与最常受累的动脉是右冠状动脉(CD)相关,占 69.6%(48 例),其次是回旋支(Cx),占 56.5%(39 例)。左心室射血分数(LVEF)平均为 47+9.72。在每个患者从 INC 出院时,都倾向于使用双重抗血小板治疗加抗凝(DAP+OAC),占 58%(40 例)。

结论

CE 在 INC 是一种不常见的病理性重塑。本研究表明,STEMI 是 CE 的最典型表现,诊断性冠状动脉造影显示 Markis 3 型,因此预计死亡率和心血管事件复发率较低,尽管对理想治疗方法尚无共识,但在 INC 倾向于个体化治疗,建议改变生活方式,并在患者出院时仅使用三联疗法(DAP+OAC)进行药物治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c22/10161814/4de1c470f13d/7567AX222-ACM-93-197-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c22/10161814/2f47445729b5/7567AX222-ACM-93-197-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c22/10161814/4de1c470f13d/7567AX222-ACM-93-197-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c22/10161814/2f47445729b5/7567AX222-ACM-93-197-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c22/10161814/4de1c470f13d/7567AX222-ACM-93-197-g002.jpg

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