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腹部器官移植:2022 年值得关注的文献。

Abdominal Organ Transplantation: Noteworthy Literature in 2022.

机构信息

Department of Anesthesiology, Perioperative and Pain Medicine, Icahn School of Medicine at Mount Sinai Hospital, New York, NY, USA.

Department of Anesthesiology and Perioperative Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

出版信息

Semin Cardiothorac Vasc Anesth. 2023 Jun;27(2):97-113. doi: 10.1177/10892532231169075. Epub 2023 Apr 10.

DOI:10.1177/10892532231169075
PMID:37037789
Abstract

This review highlights noteworthy literature published in 2022 pertinent to anesthesiologists and critical care physicians caring for patients undergoing abdominal organ transplantation. We begin by exploring the impacts that the COVID-19 pandemic has had across the field of abdominal organ transplantation, including the successful use of grafts procured from COVID-19-infected donors. In pancreatic transplantation, we highlight several studies on dexmedetomidine and ischemia-reperfusion injury, equity in transplantation, and medical management, as well as studies comparing pancreatic transplantation to islet cell transplantation. In our section on intestinal transplantation, we explore donor selection. Kidney transplantation topics include cardiovascular risk management, obesity, and intraoperative management, including fluid resuscitation, dexmedetomidine, and sugammadex. The liver transplantation section focuses on clinical trials, systematic reviews, and meta-analyses published in 2022 and covers a wide range of topics, including machine perfusion, cardiovascular issues, renal issues, and coagulation/transfusion.

摘要

这篇综述重点介绍了 2022 年发表的与麻醉师和重症监护医师照顾接受腹部器官移植患者相关的重要文献。我们首先探讨了 COVID-19 大流行对腹部器官移植领域的影响,包括成功使用来自 COVID-19 感染供体的移植物。在胰腺移植方面,我们重点介绍了几项关于右美托咪定和缺血再灌注损伤、移植公平性和医学管理的研究,以及比较胰腺移植和胰岛细胞移植的研究。在我们关于肠移植的部分,我们探讨了供体选择。肾脏移植的主题包括心血管风险管理、肥胖和术中管理,包括液体复苏、右美托咪定和 sugammadex。肝移植部分重点介绍了 2022 年发表的临床试验、系统评价和荟萃分析,涵盖了广泛的主题,包括机器灌注、心血管问题、肾脏问题和凝血/输血。

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