Solans-Lopez María C, Sanchez-Somolinos Mar, Igualada-Blazquez Cristina, Quevedo-Narciso Tania, Vicente-Herrera Edmundo, Riquelme-García Oscar, Esparragoza-Cabrera Luis
Department of Spine Surgery, Orthopaedic Surgery and Traumatology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Department of Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
J Spine Surg. 2023 Mar 30;9(1):102-108. doi: 10.21037/jss-22-81. Epub 2023 Jan 6.
() is an anaerobic Gram-positive coccus, common commensal of the gastrointestinal tract of animals and humans. Anaerobic organisms as etiologic agents of bone and joint infections (BJI) are uncommon and frequently underestimated. New technologies, such as mass spectrometry techniques and molecular techniques like 16S rRNA, allow for more efficient diagnosis of these anaerobic bacteria. We present the first case report of deep surgical site infection (SSI) due to , following spinal surgery.
We report the case of a deep SSI caused by following posterior spinal instrumentation in an 81-year-old woman. The patient underwent extension of her previous fusion L2-L5, due to adjacent segment disease (ASD). We performed a T10 to S2-alar-iliac instrumentation. During the postoperative period, the patient presented with a paralytic ileus that required the placement of a nasogastric tube followed by gastrointestinal bleeding and two gastroscopies. Subsequently the patient showed signs of deep SSI. We performed surgical irrigation and debridement. All six cultures in anaerobic media showed short Gram-positive diplococci, using matrix-assisted laser desorption/ionization time of flight mass spectrometry (Maldi-TOF MS) all six strains were identified as . The patient was treated with amoxicilin 1 g/8 h and ciprofloxacin 750 mg/12 h for 4 weeks. Six months postoperative, she was asymptomatic.
As is the case with our patient, all previously described cases of infection had a history of intestinal disease or immunosupression. We believe the isolation of should raise the possibility of intestinal injury. Immunosuppression is also an important risk factor for the development of infection.
()是一种厌氧革兰氏阳性球菌,是动物和人类胃肠道常见的共生菌。作为骨与关节感染(BJI)病原体的厌氧菌并不常见,且常被低估。新技术,如质谱技术和16S rRNA等分子技术,有助于更有效地诊断这些厌氧菌。我们报告首例脊柱手术后因()导致深部手术部位感染(SSI)的病例。
我们报告一例81岁女性在脊柱后路内固定术后因()导致深部SSI的病例。患者因相邻节段疾病(ASD)接受了先前L2-L5融合术的延长手术。我们进行了T10至S2翼状髂骨内固定术。术后期间,患者出现麻痹性肠梗阻,需要放置鼻胃管,随后出现胃肠道出血并进行了两次胃镜检查。随后患者出现深部SSI的迹象。我们进行了手术冲洗和清创。在厌氧培养基中的所有六次培养均显示革兰氏阳性短双球菌,使用基质辅助激光解吸/电离飞行时间质谱(Maldi-TOF MS)所有六个菌株均被鉴定为()。患者接受阿莫西林1 g/8小时和环丙沙星750 mg/12小时治疗4周。术后六个月,她无症状。
正如我们患者的情况一样,所有先前描述的()感染病例都有肠道疾病或免疫抑制病史。我们认为分离出()应增加肠道损伤的可能性。免疫抑制也是()感染发生的重要危险因素。