Furutani Tomoki, Kitano Hiroyuki, Ikeda Kenichiro, Shirane Satoshi, Koba Yumiko, Kashiyama Seiya, Kitagawa Hiroki, Hieda Keisuke, Ohge Hiroki, Hinata Nobuyuki
Department of Urology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima City, Japan.
Department of Clinical Practice and Support, Hiroshima University Hospital, Hiroshima City, Japan.
Heliyon. 2023 May 2;9(5):e16011. doi: 10.1016/j.heliyon.2023.e16011. eCollection 2023 May.
We report a case of bloodstream infection due to () associated with pelvic abscess in a 74-year-old female patient undergoing radiotherapy for cervical cancer. Gram staining of positive anaerobic blood cultures revealed short chains of gram-positive cocci. Matrix-assisted laser desorption ionization time-of-flight mass spectrometry was performed directly on the blood culture bottle, and 16S rRNA sequencing identified the bacterium as . There was no leakage from the sigmoid colon to rectum on enterography, and was not found in the culture of her pelvic abscess. After the administration of piperacillin/tazobactam, her condition markedly improved. This patient with infection demonstrated no gastrointestinal involvement, whereas past published cases reported diverticulitis or intestinal damage. It is possible that bacterial translocation of occurred from the gut microbiota, due to damage to the intestinal tract caused by radiation.
我们报告了一例74岁接受宫颈癌放疗的女性患者发生血流感染，该感染与盆腔脓肿相关。革兰氏阳性厌氧菌血培养的革兰氏染色显示革兰氏阳性球菌短链。直接在血培养瓶上进行基质辅助激光解吸电离飞行时间质谱分析，16S rRNA测序鉴定该细菌为 。肠道造影显示乙状结肠至直肠无渗漏，盆腔脓肿培养未发现 。给予哌拉西林/他唑巴坦后，她的病情明显改善。该 感染患者未出现胃肠道受累，而既往发表的病例报告有憩室炎或肠道损伤。由于放疗对肠道造成的损害， 可能从肠道微生物群发生细菌易位。
