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笼状三萜类化合物从人工栽培的 cf. 子实体中提取。

Lanostane triterpenoids from artificially cultivated fruiting bodies of cf. .

机构信息

National Center for Genetic Engineering and Biotechnology (BIOTEC), Klong Luang, Pathumthani, Thailand.

National Biobank of Thailand, Klong Luang, Pathumthani, Thailand.

出版信息

Nat Prod Res. 2024 Aug;38(15):2644-2652. doi: 10.1080/14786419.2023.2196723. Epub 2023 Apr 11.

Abstract

In the quest for bioactive compounds from , artificially cultivated fruiting bodies of cf. , strain TBRC-BCC 47851 were chemically investigated. The study led to the isolation of three undescribed lanostane triterpenoids () together with twelve known compounds. The structures were elucidated on the basis of NMR spectroscopic and mass spectrometry data. The new compounds were inactive in the antimalarial and antitubercular activity assays.

摘要

从 中寻找生物活性化合物时,对人工栽培的 cf. ,菌株 TBRC-BCC 47851 的子实体进行了化学研究。该研究分离得到了三种未被描述的羊毛甾烷三萜(),以及十二种已知化合物。根据 NMR 光谱和质谱数据确定了这些新化合物的结构。这些新化合物在抗疟和抗结核活性测定中均没有活性。

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