健康人群右心室心肌做功的无创超声心动图评估。
The non-invasive echocardiographic assessment of right ventricular myocardial work in a healthy population.
机构信息
Department of Ultrasonography, Xiamen Cardiovascular Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
School of Medicine, Xiamen University, Xiamen, China.
出版信息
Acta Cardiol. 2023 Jun;78(4):423-432. doi: 10.1080/00015385.2023.2189870. Epub 2023 Apr 11.
BACKGROUND
Non-invasive right ventricular (RV) myocardial work (RVMW) is the latest indicator used to assess RV function. Nevertheless, the physiological determinants of RVMW have not been studied, and reference ranges for normal RVMW indices have yet to be established.
METHODS
A total of 263 healthy volunteers (median age: 34 years, males: 38%) were prospectively enrolled. RVMW indices were analysed by an RV pressure-strain loop (RVPSL) in specific software.
RESULTS
The lowest values of the RVMW indices in males and females were 133 mmHg% and 206 mmHg% for RV global work index (RVGWI), 165 mmHg% and 241 mmHg% for RV global constructive work (RVGCW) and 78% and 83% for RV global work efficiency (RVGWE), respectively. The highest values for RV global wasted work (RVGWW) in males and females were 67 mmHg% and 69 mmHg%, respectively. RVGWI and RVGCW were significantly lower in males than those in females. RVGWW significantly increased with age in males and females. RVGWE significantly decreased with age in females. Multivariable analysis revealed that RVGWI, RVGCW and RVGWE increased as pulmonary artery systolic pressure (PASP) increased.
CONCLUSIONS
Normal reference values of non-invasive RVMW were obtained by echocardiography. Quantitative data on RVMW could be essential in clinical work and clinical experiments.
背景
无创右心室（RV）心肌做功（RVMW）是评估 RV 功能的最新指标。然而，RVMW 的生理决定因素尚未被研究，正常 RVMW 指标的参考范围尚未建立。
方法
共前瞻性纳入 263 名健康志愿者（中位年龄：34 岁，男性：38%）。RVPSL 在特定软件中分析 RVMW 指数。
结果
男性和女性 RVMW 指数的最低值分别为 RV 整体做功指数（RVGWI）的 133mmHg%和 206mmHg%，RV 整体有效做功（RVGCW）的 165mmHg%和 241mmHg%，以及 RV 整体做功效率（RVGWE）的 78%和 83%。男性和女性的 RV 整体无效做功（RVGWW）最高值分别为 67mmHg%和 69mmHg%。男性的 RVGWI 和 RVGCW 明显低于女性。男性和女性的 RVGWW 随年龄增加而增加。女性的 RVGWE 随年龄增加而降低。多变量分析显示，RVGWI、RVGCW 和 RVGWE 随着肺动脉收缩压（PASP）的增加而增加。
结论
通过超声心动图获得了无创 RVMW 的正常参考值。RVMW 的定量数据在临床工作和临床实验中可能是必不可少的。
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