Department of Ophthalmology and Visual Science, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama, Kanagawa, 236-0004, Japan.
Department of Ophthalmology, Kanagawa Children's Medical Center, 2-138-4 Mutsukawa, Minami-ku, Yokohama, Kanagawa, 232-0066, Japan.
Sci Rep. 2023 Apr 11;13(1):5857. doi: 10.1038/s41598-023-32050-4.
A multicenter randomized controlled trial was conducted to compare the effectiveness of incisional and nonincisional surgical techniques for treating lower lid epiblepharon in children. The study included 89 eyes from 50 children aged 3-15 years (mean, 7.5 ± 2.4 years) with moderate lower lid epiblepharon. Patients were randomly assigned to either incisional (modified Hotz procedure with lid margin splitting; 45 eyes of 25 patients) or nonincisional (44 eyes of 25 patients) surgery groups. Treatment outcomes and changes in astigmatism were evaluated 6 months after surgery. Incisional surgery provided a significantly higher percentage (77.8%) of well-corrected treatment results (P = 0.026; odds ratio, 2.88; 95% confidence interval, 1.07-8.22) than nonincisional surgery (55.4%). The mean change in astigmatism 6 months after surgery was - 0.24 ± 0.42 and - 0.01 ± 0.47 D in the incisional and nonincisional surgery groups, respectively. The improvement in astigmatism was significantly higher in the incisional surgery group than in the nonincisional surgery group (P = 0.008). The incisional surgical treatment for moderate epiblepharon in children resulted in a higher number of well-corrected patients, indicating an absence of both ciliary touch and superficial keratitis as well as statistically significant improvements in astigmatism correction.
一项多中心随机对照试验比较了切开和非切开手术技术治疗儿童下睑皮赘的效果。该研究纳入了 50 名 3-15 岁(平均 7.5±2.4 岁)儿童的 89 只眼,这些儿童均患有中度下睑皮赘。患者被随机分为切开组(改良 Hotz 术联合睑缘劈开术;25 例患者 45 只眼)或非切开组(25 例患者 44 只眼)。术后 6 个月评估治疗效果和散光变化。切开手术的治疗结果(77.8%)明显优于非切开手术(55.4%)(P=0.026;优势比,2.88;95%置信区间,1.07-8.22)。术后 6 个月散光的平均变化分别为-0.24±0.42 和-0.01±0.47 D,切开组的改善明显高于非切开组(P=0.008)。儿童中度皮赘的切开手术治疗产生了更多的治疗效果良好的患者,表明既没有睫状体接触也没有浅层角膜炎,并且散光矫正有显著的统计学改善。