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比较两种手术技术治疗儿童下眼睑皮赘的效果:一项随机对照试验。

Comparing the effectiveness of two surgical techniques for treating lower lid epiblepharon in children: a randomized controlled trial.

机构信息

Department of Ophthalmology and Visual Science, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama, Kanagawa, 236-0004, Japan.

Department of Ophthalmology, Kanagawa Children's Medical Center, 2-138-4 Mutsukawa, Minami-ku, Yokohama, Kanagawa, 232-0066, Japan.

出版信息

Sci Rep. 2023 Apr 11;13(1):5857. doi: 10.1038/s41598-023-32050-4.

DOI:10.1038/s41598-023-32050-4
PMID:37041260
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10090162/
Abstract

A multicenter randomized controlled trial was conducted to compare the effectiveness of incisional and nonincisional surgical techniques for treating lower lid epiblepharon in children. The study included 89 eyes from 50 children aged 3-15 years (mean, 7.5 ± 2.4 years) with moderate lower lid epiblepharon. Patients were randomly assigned to either incisional (modified Hotz procedure with lid margin splitting; 45 eyes of 25 patients) or nonincisional (44 eyes of 25 patients) surgery groups. Treatment outcomes and changes in astigmatism were evaluated 6 months after surgery. Incisional surgery provided a significantly higher percentage (77.8%) of well-corrected treatment results (P = 0.026; odds ratio, 2.88; 95% confidence interval, 1.07-8.22) than nonincisional surgery (55.4%). The mean change in astigmatism 6 months after surgery was - 0.24 ± 0.42 and - 0.01 ± 0.47 D in the incisional and nonincisional surgery groups, respectively. The improvement in astigmatism was significantly higher in the incisional surgery group than in the nonincisional surgery group (P = 0.008). The incisional surgical treatment for moderate epiblepharon in children resulted in a higher number of well-corrected patients, indicating an absence of both ciliary touch and superficial keratitis as well as statistically significant improvements in astigmatism correction.

摘要

一项多中心随机对照试验比较了切开和非切开手术技术治疗儿童下睑皮赘的效果。该研究纳入了 50 名 3-15 岁(平均 7.5±2.4 岁)儿童的 89 只眼,这些儿童均患有中度下睑皮赘。患者被随机分为切开组(改良 Hotz 术联合睑缘劈开术;25 例患者 45 只眼)或非切开组(25 例患者 44 只眼)。术后 6 个月评估治疗效果和散光变化。切开手术的治疗结果(77.8%)明显优于非切开手术(55.4%)(P=0.026;优势比,2.88;95%置信区间,1.07-8.22)。术后 6 个月散光的平均变化分别为-0.24±0.42 和-0.01±0.47 D,切开组的改善明显高于非切开组(P=0.008)。儿童中度皮赘的切开手术治疗产生了更多的治疗效果良好的患者,表明既没有睫状体接触也没有浅层角膜炎,并且散光矫正有显著的统计学改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f31/10090162/1b286d770c32/41598_2023_32050_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f31/10090162/1b286d770c32/41598_2023_32050_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f31/10090162/1b286d770c32/41598_2023_32050_Fig1_HTML.jpg

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本文引用的文献

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Br J Ophthalmol. 2018 Nov;102(11):1504-1509. doi: 10.1136/bjophthalmol-2017-311635. Epub 2018 Mar 21.
2
Effects of epiblepharon surgery on higher-order aberrations.睑缘内翻手术对高阶像差的影响。
J AAPOS. 2016 Jun;20(3):226-31. doi: 10.1016/j.jaapos.2016.01.015. Epub 2016 May 6.
3
Modified Hotz Procedure Combined With Modified Z-Epicanthoplasty Versus Modified Hotz Procedure Alone for Epiblepharon Repair.
改良霍茨手术联合改良Z形内眦赘皮矫正术与单纯改良霍茨手术治疗睑内翻的比较
Ophthalmic Plast Reconstr Surg. 2017 Mar/Apr;33(2):120-123. doi: 10.1097/IOP.0000000000000664.
4
Medial lower lid epiblepharon repair solely by skin-redraping medial epicanthoplasty.单纯经皮重睑皱襞法行下睑内侧皮瓣转移矫正内眦赘皮
Br J Ophthalmol. 2014 Oct;98(10):1437-41. doi: 10.1136/bjophthalmol-2014-304884. Epub 2014 May 22.
5
Is it truly necessary to add epicanthoplasty for correction of the epiblepharon?对于睑裂斑炎的矫正,真的有必要增加内眦成形术吗?
J Craniofac Surg. 2013 Jul;24(4):1137-40. doi: 10.1097/SCS.0b013e3182801d2f.
6
The effect of epiblepharon surgery on visual acuity and with-the-rule astigmatism in children.儿童睑缘内翻手术对视力及顺规散光的影响。
Korean J Ophthalmol. 2010 Dec;24(6):325-30. doi: 10.3341/kjo.2010.24.6.325. Epub 2010 Nov 23.
7
[Epicanthoplasty simultaneous with epiblepharoplasty in cases of epiblepharon with epicanthus].[内眦赘皮合并睑缘内翻病例中行内眦成形术同期行睑缘修复术]
Nippon Ganka Gakkai Zasshi. 2010 Feb;114(2):105-9.
8
Epiblepharon in East asian patients: the singapore experience.东亚患者的眼睑内翻:新加坡的经验。
Ophthalmology. 2010 Jan;117(1):184-9. doi: 10.1016/j.ophtha.2009.06.044. Epub 2009 Nov 5.
9
Changes in astigmatism after surgery for epiblepharon in highly astigmatic children: a controlled study.高度散光儿童睑裂斑手术后散光的变化:一项对照研究。
J AAPOS. 2008 Dec;12(6):597-601. doi: 10.1016/j.jaapos.2008.06.010. Epub 2008 Oct 4.
10
The effect of surgical correction of epiblepharon on astigmatism in children.儿童睑缘内翻手术矫正对散光的影响。
J Pediatr Ophthalmol Strabismus. 2008 Jan-Feb;45(1):31-5. doi: 10.3928/01913913-20080101-18.