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老年心力衰竭患者首发事件后一年内循环系统疾病再入院和住院死亡率。西班牙 2016 年至 2018 年期间公立医院的全国范围数据。

One-year readmissions for circulatory diseases and in-hospital mortality after an index episode of heart failure in elderly patients. A nationwide data from public hospitals in Spain between 2016 and 2018.

机构信息

Cardiology Service, Hospital Universitario Severo Ochoa, Calle Orellana S/N, 28911, Leganés, Madrid, Spain.

Cardiology Service, Hospital Universitario Reina Sofía, Córdoba, Spain.

出版信息

Clin Res Cardiol. 2023 Aug;112(8):1119-1128. doi: 10.1007/s00392-023-02202-7. Epub 2023 Apr 11.

Abstract

INTRODUCTION

Heart failure (HF) is one of the leading causes of hospitalization and death in elderly patients. However, there is limited evidence on readmission and mortality 1-year after discharge for HF.

METHODS

Retrospective analysis of the Minimum Basic Data Set, including HF episodes, discharged from Spanish hospitals between 2016 and 2018 in ≥ 75 years. We calculated: (a) the rate of readmissions due to circulatory system diseases (CSD) 365 days after index episode; (b) in-hospital mortality in readmissions; and (c) predictors of mortality and readmission.

RESULTS

We included 178,523 patients (59.2% women) aged 85.1 ± 5.5 years. The most frequent comorbidities were arrhythmias (56.0%) and renal failure (39.5%). During the follow-up, 48,932 patients (27.4%) had at least one readmission for CSD and a crude rate of 40.2%, the most frequent one HF (52.8%). The median between the date of readmission and discharge from the last admission was 70 days [IQI 24; 171] for the first readmission. The most relevant predictors of the number of readmissions were valvular heart disease and myocardial ischemia. During the readmissions, 26,757 patients (79.1%) died, representing a cumulative in-hospital mortality of 47,945 (26.9%). The factors in the index episode predictors of mortality during readmissions were cardio-respiratory failure and stroke. The number of readmissions was a risk factor for in-hospital mortality (OR 1.13; 95% CI 1.11-1.14).

CONCLUSIONS

The readmission rate for CSD 1-year after the index episode of HF in patients ≥ 75 years was 28.4%. The cumulative in-hospital mortality rate during the readmissions was 26.9%, and the number of rehospitalizations was identified as one of the main predictors of mortality.

摘要

引言

心力衰竭(HF)是导致老年患者住院和死亡的主要原因之一。然而,关于 HF 出院后 1 年的再入院和死亡率的证据有限。

方法

回顾性分析了西班牙医院 2016 年至 2018 年间≥75 岁的 HF 患者的最低基本数据集,包括 HF 发作。我们计算了:(a)索引发作后 365 天因循环系统疾病(CSD)再入院的比率;(b)再入院中的院内死亡率;和(c)死亡率和再入院的预测因素。

结果

我们纳入了 178523 名(59.2%为女性)年龄 85.1±5.5 岁的患者。最常见的合并症是心律失常(56.0%)和肾功能衰竭(39.5%)。在随访期间,48932 名(27.4%)患者至少有一次因 CSD 再入院,粗再入院率为 40.2%,最常见的再入院原因是 HF(52.8%)。第一次再入院的中位时间为出院后再入院日期和最后一次入院出院日期之间的中位数为 70 天[IQR 24;171]。再入院次数的最相关预测因素是瓣膜性心脏病和心肌缺血。在再入院期间,26757 名(79.1%)患者死亡,累计院内死亡率为 47945(26.9%)。再入院期间预测死亡率的指数发作预测因素是心肺衰竭和中风。再入院次数是院内死亡率的危险因素(OR 1.13;95%CI 1.11-1.14)。

结论

≥75 岁患者 HF 指数发作后 1 年 CSD 的再入院率为 28.4%。再入院期间的累计院内死亡率为 26.9%,再入院次数被确定为死亡率的主要预测因素之一。

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