Pokrovskiĭ A V, Dmitrieva V A, Aleksandrova N P, Kovalenko V I, Il'in S G
Kardiologiia. 1979 Feb;19(2):54-61.
The initial hemorheologic values and their dynamics in various periods after reconstructive operations were studied in 70 patients with atherosclerosis of the abdominal aorta. The rheologic blood properties proved to be considerably changed in atherosclerotic affection of the abdominal aorta. The causes of the hemorheologic disorders in this pathological condition are marked changes in regional hemodynamics and the character of the blood flow and significant disorders of protein, lipid and carbohydrate metabolism. Study of the effect of aspirin on the rheologic properties of blood in this contingent of patients showed the expediency of its use both in preoperative management and in the postoperative period. Aspirin reduces significantly the degree of blood platelet aggregation and the seeming viscosity of blood.
对70例腹主动脉粥样硬化患者重建手术后不同时期的初始血液流变学值及其动态变化进行了研究。结果证明,腹主动脉粥样硬化时血液流变学特性发生了显著改变。这种病理状态下血液流变学紊乱的原因是局部血流动力学和血流特性的明显改变以及蛋白质、脂质和碳水化合物代谢的显著紊乱。对这组患者中阿司匹林对血液流变学特性影响的研究表明,在术前处理和术后阶段使用阿司匹林都是适宜的。阿司匹林能显著降低血小板聚集程度和血液表观粘度。