采用移植后环磷酰胺的单倍体相合异基因干细胞移植及后续肾移植治疗终末期肾病（ESKD）的重症镰状细胞病患者。 - Suppr

Haploidentical allogeneic stem cell transplantation with post-transplant cyclophosphamide and subsequent kidney transplant for patients with severe sickle cell disease with end-stage kidney disease (ESKD).

作者信息

Gomez-Arteaga Alexandra, Orfali Nina, Pasciolla Michelle, Baptiste Ayanna, Guindine Inna, Hsu Jingmei, Lin Jonathan, Mayer Sebastian A, Phillips Adrienne A, Shore Tsiporah B, Simonson Paul D, DiCarlo Edward, Yoon Sung, Muthukumar Thangamani, van Besien Koen

机构信息

Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine, NewYork-Presbyterian Hospital, New York, NY, USA.

Department of Haematology, St James Hospital, Dublin, Ireland.

出版信息

Bone Marrow Transplant. 2023 Jul;58(7):835-838. doi: 10.1038/s41409-023-01981-x. Epub 2023 Apr 12.

DOI:10.1038/s41409-023-01981-x

PMID:37045941

Abstract

摘要

相似文献

Haploidentical allogeneic stem cell transplantation with post-transplant cyclophosphamide and subsequent kidney transplant for patients with severe sickle cell disease with end-stage kidney disease (ESKD).采用移植后环磷酰胺的单倍体相合异基因干细胞移植及后续肾移植治疗终末期肾病（ESKD）的重症镰状细胞病患者。

Bone Marrow Transplant. 2023 Jul;58(7):835-838. doi: 10.1038/s41409-023-01981-x. Epub 2023 Apr 12.

Reduced toxicity, myeloablative HLA-haploidentical hematopoietic stem cell transplantation with post-transplantation cyclophosphamide for sickle cell disease.降低毒性的清髓性人类白细胞抗原半相合造血干细胞移植联合移植后环磷酰胺治疗镰状细胞病

Ann Hematol. 2017 Aug;96(8):1373-1377. doi: 10.1007/s00277-017-3030-x. Epub 2017 Jun 1.

Haploidentical Allogeneic Stem Cell Transplantation in Sickle Cell Disease: A Systematic Review and Meta-Analysis.《镰状细胞病中同单体异体造血干细胞移植：系统评价和荟萃分析》。

Transplant Cell Ther. 2021 Dec;27(12):1004.e1-1004.e8. doi: 10.1016/j.jtct.2021.09.009. Epub 2021 Sep 17.

Haploidentical hematopoietic stem cell transplant for patients with sickle cell disease using thiotepa, fludarabine, thymoglobulin, low dose cyclophosphamide, 200 cGy tbi and post transplant cyclophosphamide.使用噻替派、氟达拉滨、抗胸腺细胞球蛋白、低剂量环磷酰胺、200厘戈瑞全身照射及移植后环磷酰胺对镰状细胞病患者进行单倍体相合造血干细胞移植。

Bone Marrow Transplant. 2018 May;53(5):647-650. doi: 10.1038/s41409-017-0077-1. Epub 2018 Jan 16.

Pre-transplant myeloid and immune suppression, upfront plerixafor mobilization and post-transplant cyclophosphamide: novel strategy for haploidentical transplant in sickle cell disease.移植前髓系和免疫抑制、预先使用普乐沙福动员及移植后环磷酰胺：镰状细胞病单倍体相合移植的新策略

Bone Marrow Transplant. 2021 Feb;56(2):492-504. doi: 10.1038/s41409-020-01054-3. Epub 2020 Sep 15.

Nonmyeloablative HLA-matched sibling allogeneic hematopoietic stem cell transplantation for severe sickle cell phenotype.非清髓性 HLA 匹配同胞供体异基因造血干细胞移植治疗严重镰状细胞表型。

JAMA. 2014 Jul 2;312(1):48-56. doi: 10.1001/jama.2014.7192.

Outcomes of Unrelated Donor Stem Cell Transplantion with Post-Transplant Cyclophosphamide for Graft-versus-Host Disease Prophylaxis in Patients with Severe Sickle Cell Disease.异基因造血干细胞移植后应用环磷酰胺预防严重镰状细胞病患者移植物抗宿主病的结果。

Biol Blood Marrow Transplant. 2018 Feb;24(2):413-417. doi: 10.1016/j.bbmt.2017.10.030. Epub 2017 Oct 20.

Haploidentical hematopoietic bone marrow transplantation followed by living kidney transplantation from the same donor in a sickle cell disease patient with end-stage renal failure.在一名患有终末期肾衰竭的镰状细胞病患者中，先进行单倍体相合造血干细胞移植，随后接受来自同一供体的活体肾移植。

Ann Hematol. 2017 Apr;96(4):703-705. doi: 10.1007/s00277-017-2936-7. Epub 2017 Feb 3.

Fludarabine-based conditioning for allogeneic transplantation in adults with sickle cell disease.基于氟达拉滨的预处理方案用于成年镰状细胞病患者的异基因移植。

Bone Marrow Transplant. 2000 Aug;26(4):445-9. doi: 10.1038/sj.bmt.1702518.

HLA-Haploidentical Hematopoietic Cell Transplantation for Treatment of Nonmalignant Diseases Using Nonmyeloablative Conditioning and Post-Transplant Cyclophosphamide.HLA 单倍体相合造血细胞移植治疗非恶性疾病：非清髓预处理和移植后环磷酰胺方案

Biol Blood Marrow Transplant. 2020 Jul;26(7):1332-1341. doi: 10.1016/j.bbmt.2020.03.018. Epub 2020 Mar 28.

本文引用的文献

How I treat sickle cell disease with hematopoietic cell transplantation.我如何用造血干细胞移植治疗镰状细胞病。

Blood. 2019 Dec 19;134(25):2249-2260. doi: 10.1182/blood.2019000821.

Haploidentical hematopoietic cell and kidney transplantation for hematological malignancies and end-stage renal failure.单倍体造血细胞和肾移植治疗血液系统恶性肿瘤和终末期肾衰竭。

Blood. 2019 Jul 11;134(2):211-215. doi: 10.1182/blood.2019000775. Epub 2019 May 31.

Effect of increased dose of total body irradiation on graft failure associated with HLA-haploidentical transplantation in patients with severe haemoglobinopathies: a prospective clinical trial.增加全身照射剂量对重度血红蛋白病患者HLA单倍型移植相关移植物失败的影响：一项前瞻性临床试验。

Lancet Haematol. 2019 Apr;6(4):e183-e193. doi: 10.1016/S2352-3026(19)30031-6. Epub 2019 Mar 14.

Haploidentical Bone Marrow Transplantation with Post-Transplantation Cyclophosphamide Plus Thiotepa Improves Donor Engraftment in Patients with Sickle Cell Anemia: Results of an International Learning Collaborative.相合亲缘骨髓移植联合移植后环磷酰胺和噻替哌可改善镰状细胞贫血患者的供者植入：国际学习合作的结果。

Biol Blood Marrow Transplant. 2019 Jun;25(6):1197-1209. doi: 10.1016/j.bbmt.2018.11.027. Epub 2018 Nov 28.

Preparative regimen dosing for hematopoietic stem cell transplantation in patients with chronic kidney disease: analysis of the literature and recommendations.慢性肾脏病患者造血干细胞移植的预处理方案剂量：文献分析与建议

Biol Blood Marrow Transplant. 2014 Jul;20(7):908-19. doi: 10.1016/j.bbmt.2014.02.013. Epub 2014 Feb 22.

Successful allogeneic stem-cell transplantation in a patient with myelodysplastic syndrome with hemodialysis-dependent end-stage renal disease.一名患有骨髓增生异常综合征且依赖血液透析的终末期肾病患者成功进行了异基因干细胞移植。

Transplantation. 2011 Sep 27;92(6):e28-9. doi: 10.1097/TP.0b013e31822a79f1.

Allogeneic stem cell transplant in renal failure: engraftment and prolonged survival, but high incidence of neurologic toxicity.异基因干细胞移植治疗肾衰竭：植入成功且生存期延长，但神经毒性发生率高。

Leuk Lymphoma. 2012 Jan;53(1):158-9. doi: 10.3109/10428194.2011.604756. Epub 2011 Sep 6.

Fludarabine-based nonmyeloablative stem cell transplantation for sickle cell disease with and without renal failure: clinical outcome and pharmacokinetics.基于氟达拉滨的非清髓性干细胞移植治疗伴或不伴肾衰竭的镰状细胞病：临床结果和药代动力学

Biol Blood Marrow Transplant. 2007 Dec;13(12):1422-6. doi: 10.1016/j.bbmt.2007.08.050.

Dialysate concentration and pharmacokinetics of 2F-Ara-A in a patient with acute renal failure.急性肾衰竭患者中2F-阿糖腺苷的透析液浓度及药代动力学

Eur J Haematol. 2005 Jun;74(6):533-4. doi: 10.1111/j.1600-0609.2005.00439.x.

Fludarabine-based conditioning for allogeneic transplantation in adults with sickle cell disease.基于氟达拉滨的预处理方案用于成年镰状细胞病患者的异基因移植。

Bone Marrow Transplant. 2000 Aug;26(4):445-9. doi: 10.1038/sj.bmt.1702518.

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Haploidentical allogeneic stem cell transplantation with post-transplant cyclophosphamide and subsequent kidney transplant for patients with severe sickle cell disease with end-stage kidney disease (ESKD).

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