Esposito Cecilia Maria, Auxilia Anna Maria, Ceresa Alessandro, Zanvit Francesco Giuseppe, Zanelli Quarantini Francesco, Capuzzi Enrico, Caldiroli Alice, Clerici Massimo, Buoli Massimiliano
Department of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Department of Medicine and Surgery, University of Milano Bicocca, Monza, Italy.
Early Interv Psychiatry. 2023 Dec;17(12):1216-1221. doi: 10.1111/eip.13429. Epub 2023 Apr 12.
Borderline personality disorder (BPD) is a prevalent condition associated with high rates of hospitalizations. The purpose of this manuscript was to detect the factors associated with duration of untreated illness (DUI) in BPD.
Through chart review, we identified 152 patients followed up by community psychiatry services in Milan and Monza, Italy. The association between DUI and socioeconomic and clinical variables was examined using Pearson correlation and analyses of variances. The statistically significant variables from univariate analyses were then inserted in regression models.
A longer DUI was associated with several variables (substance misuse after the onset of BPD, older age, earlier age at onset, longer duration of illness), but these results were not maintained in the regression analyses.
In conclusion, DUI does not seem to be significantly associated with specific clinical aspects of BPD, or significantly modify the course and outcome of the disorder. Studies with larger samples have to confirm these preliminary findings.
边缘性人格障碍（BPD）是一种普遍存在的疾病，与高住院率相关。本手稿的目的是检测与BPD未治疗疾病持续时间（DUI）相关的因素。
通过病历审查，我们确定了152名在意大利米兰和蒙扎接受社区精神病学服务随访的患者。使用Pearson相关性和方差分析检查DUI与社会经济和临床变量之间的关联。然后将单变量分析中具有统计学意义的变量纳入回归模型。
较长的DUI与几个变量相关（BPD发病后物质滥用、年龄较大、发病年龄较早、病程较长），但这些结果在回归分析中未得到维持。
总之，DUI似乎与BPD的特定临床方面没有显著关联，也没有显著改变该疾病的病程和结局。需要更大样本的研究来证实这些初步发现。
