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使用带远端动静脉瘘插入的人工血管进行膝下旁路移植的长期结果

Long-Term Results of Below-The-Knee Bypass Using a Prosthetic Graft with a Distal Arteriovenous Fistula Interposition.

作者信息

Spinelli Francesco, Roscitano Giuseppe, Barillà David, Derone Graziana, Nenna Antonio, Montelione Nunzio, Catanese Vincenzo, Cutrupi Andrea, Giambra Martina Maria, Varrà Alessandra, Veroux Pier Francesco, Stilo Francesco

机构信息

Division of Vascular Surgery, Department of Medicine and Surgery, University Hospital Foundation Campus Bio-Medico, 00128 Rome, Italy.

Department of General Surgery and Medical Specialties, University of Catania, 95100 Catania, Italy.

出版信息

Diagnostics (Basel). 2023 Mar 26;13(7):1246. doi: 10.3390/diagnostics13071246.

DOI:10.3390/diagnostics13071246
PMID:37046465
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10093735/
Abstract

Surgical bypass is the gold standard treatment in patients affected by chronic limb-threatening ischemia in advanced GLASS stages, according to the Global Vascular Guidelines. For patients in whom an autologous graft is not available, a prosthesis could be used with the adjunct of a distal arteriovenous fistula interposition. The aim of this study was to examine the long-term results of below-the-knee surgical revascularization using a prosthesis with the distal adjunct mentioned above. From 2010 to 2020, we performed 159 lower limb below-the-knee surgical revascularizations using a prosthesis with the creation of an arteriovenous fistula interposition on the distal anastomosis. The GLASS stage was 3 in 100% of patients. The primary patency rates were as follows: 86.7% at 1 year, 57.2% at 3 years, and 12.6% at 5 years. The graft thrombosis rates were 17.4% at 1 year, 42.1% at 3 years, and 64.5% at 5 years. The amputation-free survival rates were 79% at 1 year, 76% at 3 years, and 64% at 5 years. PTFE prosthetic bypass for below-the-knee arteries using an arteriovenous fistula interposition is a good solution in patients without an autologous conduit. This technique offers reasonable graft patency and limb salvage rates.

摘要

根据全球血管指南,手术旁路是晚期全球肢体解剖分期系统(GLASS)中慢性肢体威胁性缺血患者的金标准治疗方法。对于无法使用自体移植物的患者,可以使用假体并辅以远端动静脉瘘插入术。本研究的目的是探讨使用上述远端辅助假体进行膝下手术血运重建的长期效果。2010年至2020年,我们对159例下肢进行了膝下手术血运重建,使用假体并在远端吻合处创建动静脉瘘。所有患者的GLASS分期均为3期。主要通畅率如下:1年时为86.7%,3年时为57.2%,5年时为12.6%。移植物血栓形成率1年时为17.4%,3年时为42.1%,5年时为64.5%。无截肢生存率1年时为79%,3年时为76%,5年时为64%。对于没有自体血管的患者,使用动静脉瘘插入术的聚四氟乙烯(PTFE)假体旁路治疗膝下动脉是一种很好的解决方案。该技术提供了合理的移植物通畅率和肢体挽救率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b3d/10093735/b52c6bdabf0f/diagnostics-13-01246-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b3d/10093735/432829b08ca9/diagnostics-13-01246-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b3d/10093735/9839491b68c8/diagnostics-13-01246-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b3d/10093735/53941e5a1e2f/diagnostics-13-01246-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b3d/10093735/3be1d693c8a9/diagnostics-13-01246-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b3d/10093735/0dba1fe97209/diagnostics-13-01246-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b3d/10093735/b52c6bdabf0f/diagnostics-13-01246-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b3d/10093735/432829b08ca9/diagnostics-13-01246-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b3d/10093735/9839491b68c8/diagnostics-13-01246-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b3d/10093735/53941e5a1e2f/diagnostics-13-01246-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b3d/10093735/3be1d693c8a9/diagnostics-13-01246-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b3d/10093735/0dba1fe97209/diagnostics-13-01246-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b3d/10093735/b52c6bdabf0f/diagnostics-13-01246-g006.jpg

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本文引用的文献

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Global Vascular Guidelines on the Management of Chronic Limb-Threatening Ischemia.全球血管指南:慢性肢体威胁性缺血的管理。
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Functional prognosis of critical limb ischemia and efficacy of restoration of direct flow below the ankle.严重下肢缺血的功能预后及踝关节以下直接血流恢复的疗效
Vascular. 2019 Feb;27(1):38-45. doi: 10.1177/1708538118798886. Epub 2018 Sep 7.
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A systematic review and meta-analysis of revascularization outcomes of infrainguinal chronic limb-threatening ischemia.
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