Nurdillah Idris, Rizuana Iqbal Hussain, Syazarina Sharis Osman
Department of Radiology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Center, Jalan Yaakob Latif, Kuala Lumpur 56000, Malaysia.
Diagnostics (Basel). 2023 Mar 27;13(7):1254. doi: 10.3390/diagnostics13071254.
Intradural extramedullary (IDEM) tumors are the most commonly observed intraspinal tumors, comprising over 60% of tumors found within the spinal canal, and the vast majority of these lesions are benign lesions. IDEM metastases are rare, but if they occur, they commonly manifest as leptomeningeal disease, secondary to drop lesions from intracranial metastases from adenocarcinomas of the lung, prostate cancer, breast cancer, melanoma, or rarely, as a result of lymphomas. The purely non-neurogenic origin of IDEM metastases is rare. Herein, we describe a patient with a previous history of treated colon cancer who presented with a progressive neurological deficit and whose imaging revealed multiple intradural, extramedullary and osseous lesions at the cervical and thoracolumbar spines. With the previous known primary and multiplicity of the lesions, an initial diagnosis of spinal metastasis was made, But it was proven to be schwannoma on histology. We emphasize the diagnostic dilemma in this case and the importance of detecting subtle imaging findings, which may be helpful to differentiate between metastatic disease and a second primary tumor.
硬脊膜内髓外(IDEM)肿瘤是最常见的脊髓内肿瘤,占椎管内肿瘤的60%以上,并且这些病变绝大多数是良性病变。IDEM转移瘤罕见,但如果发生,通常表现为软脑膜疾病,继发于肺癌、前列腺癌、乳腺癌、黑色素瘤的颅内转移瘤的播散性病变,或很少见的淋巴瘤所致。IDEM转移瘤纯粹起源于非神经源性的情况罕见。在此,我们描述一名既往有结肠癌治疗史的患者,该患者出现进行性神经功能缺损,影像学检查显示颈段和胸腰段脊柱有多个硬脊膜内、髓外及骨质病变。鉴于既往已知的原发肿瘤及病变的多发性,初步诊断为脊柱转移瘤,但组织学检查证实为神经鞘瘤。我们强调该病例中的诊断困境以及检测细微影像学表现的重要性,这可能有助于鉴别转移性疾病和第二原发性肿瘤。