Whitehill R, Wilhelm C E, Moskal J T, Kramer S J, Ruch W W
Spine (Phila Pa 1976). 1986 Jan-Feb;11(1):6-13. doi: 10.1097/00007632-198601000-00003.
In an attempt to enhance the immediate stability of posterior interspinous fusion constructs, the authors conducted the following project. Twenty-four adult mongrel dogs underwent a posterior C4-C5 fusion using iliac crest autogenous graft and internal fixation using either ulna struts (12) or metallic struts (12) fixed into position by sublaminar wires. Half of the animals were killed at either 1 week or 3 months postoperatively, and their C4-C5 motion segments were excised and studied radiologically, mechanically, and histologically. Both fusions created immediate and 3-month stability equivalent or superior to normal C4-C5 canine spinal segments. However, three dogs were rendered completely and two dogs incompletely quadriplegic by the surgery.
Because of the relatively high rate of neurologic injury associated with these procedures in normal dogs, the authors hesitate to endorse their use in all but complete quadriplegic patients.
为了增强棘突间后路融合结构的即时稳定性，作者开展了以下项目。24只成年杂种犬接受了C4 - C5后路融合术，使用自体髂骨移植，并采用尺骨支撑物（12只）或金属支撑物（12只）通过椎板下钢丝固定于相应位置进行内固定。一半动物在术后1周或3个月处死，切除其C4 - C5运动节段并进行放射学、力学和组织学研究。两种融合方式均产生了即时稳定性以及3个月后的稳定性，等同于或优于正常犬C4 - C5脊髓节段。然而，手术导致3只犬完全四肢瘫痪，2只犬不完全四肢瘫痪。
由于在正常犬中这些手术相关的神经损伤发生率相对较高，作者对于除完全性四肢瘫痪患者外的其他患者使用这些手术持谨慎态度。
