Skibber J M, Lotze M T, Garra B, Fauci A
Surgery. 1986 May;99(5):626-30.
Chronic granulomatous disease (CGD) is a disorder of polymorphonuclear leukocytes that can cause multiple recurrent hepatic abscesses in 40% of those patients with the disorder. The mortality rate from this complication of CGD is estimated at 27%. Treatment has consisted of extensive surgical debridement and drainage and prolonged antibiotic therapy; however, this approach is accompanied by high morbidity and the frequent need for reoperation. Successful percutaneous drainage of multiple hepatic abscesses in a patient who had previously undergone 10 operative procedures to manage hepatic abscesses is reported. With the development of imaging and percutaneous drainage techniques, as well as the recurrent nature of this problem, percutaneous management should be given consideration in appropriate patients with CGD with hepatic abscesses.
慢性肉芽肿病(CGD)是一种多形核白细胞疾病,40%的患者会出现多发性复发性肝脓肿。据估计,CGD这种并发症的死亡率为27%。治疗方法包括广泛的手术清创引流和长期抗生素治疗;然而,这种方法伴随着高发病率和频繁的再次手术需求。本文报道了一名患者成功进行经皮引流多发性肝脓肿,该患者此前已接受10次手术治疗肝脓肿。随着影像学和经皮引流技术的发展,以及该问题的复发性,对于合适的患有肝脓肿的CGD患者,应考虑采用经皮治疗。