Zhang Yizhong, Fan Xinqi, Liang Du, Guo Qi, Zhang Xiaojuan, Nie Mengen, Li Chunhong, Meng Shan, Zhang Xianggui, Xu Peng, Guo Wenqi, Wang Huiyan, Liu Qingshan, Wu Yuxiang
College of Agriculture, Shanxi Agricultural University, Taigu 030801, China.
Sorghum Research Institute, Shanxi Key Laboratory of Sorghum Genetic and Germplasm Innovation, Shanxi Agricultural University, Yuci 030600, China.
Plants (Basel). 2023 Apr 4;12(7):1557. doi: 10.3390/plants12071557.
(L.) is one of the oldest crops cultivated by human beings which has been used in food and wine making. To understand the genetic diversity of sorghum breeding resources and further guide molecular-marker-assisted breeding, six yield-related traits were analyzed for 214 sorghum germplasm from all over the world, and 2,811,016 single-nucleotide polymorphisms (SNPs) markers were produced by resequencing these germplasms. After controlling Q and K, QTLs were found to be related to the traits using three algorisms. Interestingly, an important QTL was found which may affect multiple traits in this study. It was the most likely candidate gene for the gene , which was a homolog of gene- found by analyzing the annotation of the gene in the LD block. The haplotype analysis showed that the was the elite haplotype, and it only existed in Chinese germplasms. The traits were proven to be more associated with the SNPs of the promoter through gene association studies. Overall, the QTLs and the genes identified in this study would benefit molecular-assisted yield breeding in sorghum.
（L.）是人类种植历史最悠久的作物之一，一直被用于食品和酿酒。为了解高粱育种资源的遗传多样性并进一步指导分子标记辅助育种，对来自世界各地的214份高粱种质的六个产量相关性状进行了分析，并通过对这些种质进行重测序产生了2,811,016个单核苷酸多态性（SNP）标记。在控制Q和K之后，使用三种算法发现了与这些性状相关的QTL。有趣的是，在本研究中发现了一个可能影响多个性状的重要QTL。通过分析LD块中该基因的注释，它是该基因最有可能的候选基因，该基因是 基因的同源物。单倍型分析表明， 是优良单倍型，且仅存在于中国种质中。通过基因关联研究证明这些性状与 启动子的SNP更相关。总体而言，本研究中鉴定出的QTL和基因将有助于高粱的分子辅助产量育种。
