Iqbal Humzah, Maharaj Dashmeet, Chaudhry Hunza, Gulati Alakh, Roytman Marina
Department of Internal Medicine, University of California, San Francisco, Fresno, CA, USA.
Department of Gastroenterology and Hepatology, University of California, San Francisco, Fresno, CA, USA.
SAGE Open Med Case Rep. 2023 Apr 6;11:2050313X231164856. doi: 10.1177/2050313X231164856. eCollection 2023.
Upper gastrointestinal tract bleeding is a common condition that can cause hemodynamic instability and death if left untreated. Endoscopic hemostasis is often successful; however, some patients may develop refractory bleeding. Pharmacologic management with octreotide is beneficial in patients with variceal bleeding and has been shown in some studies to be effective in refractory bleeding due to angiodysplasia. There is a paucity of literature regarding the usage of long-term octreotide in refractory bleeding secondary to a peptic ulcer. We present a case of a bleeding gastric ulcer that was refractory to endoscopic management but responsive to long-term octreotide therapy.
上消化道出血是一种常见病症,如果不进行治疗,可能会导致血流动力学不稳定并危及生命。内镜止血通常是成功的;然而,一些患者可能会出现难治性出血。奥曲肽的药物治疗对静脉曲张出血患者有益,并且一些研究表明其对血管发育异常引起的难治性出血有效。关于长期使用奥曲肽治疗消化性溃疡继发难治性出血的文献较少。我们报告一例出血性胃溃疡患者,该患者对内镜治疗无效,但对长期奥曲肽治疗有反应。