GPI 锚：按需调控。
GPI anchors: Regulated as needed.
机构信息
Department of Cell Biology, Faculty of Biology, University of Seville, Seville, Spain.
Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío/Consejo Superior de Investigaciones Científicas/Universidad de Sevilla , Seville, Spain.
出版信息
J Cell Biol. 2023 May 1;222(5). doi: 10.1083/jcb.202303097. Epub 2023 Apr 13.
Abstract
GPI anchoring is an essential post-translational modification in eukaryotes that links proteins to the plasma membrane. In this issue, Liu et al. (2023. J. Cell Biol.https://doi.org/10.1083/jcb.202208159) suggest, for the first time, a regulation on demand of the GPI glycolipid precursor biosynthesis.
摘要
糖基磷脂酰肌醇（GPI）锚定是真核生物中一种重要的翻译后修饰过程，它将蛋白质与质膜连接在一起。在本期中，Liu 等人（2023. J. Cell Biol. https://doi.org/10.1083/jcb.202208159）首次提出了一种对 GPI 糖脂前体生物合成的按需调节机制。
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