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儿童游离腓骨血管化重建下颌骨的长期疗效。

Long-Term Outcomes after Pediatric Mandibular Reconstruction Using Vascularized Free Fibula Flap.

机构信息

From the Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology; National Center of Stomatology; National Clinical Research Center for Oral Diseases; and National Engineering Laboratory for Digital and Material Technology of Stomatology.

出版信息

Plast Reconstr Surg. 2024 Feb 1;153(2):397e-406e. doi: 10.1097/PRS.0000000000010529. Epub 2023 Apr 13.

Abstract

BACKGROUND

The purpose of this study was to evaluate the long-term outcomes of mandibular reconstruction with vascularized free fibula flap in pediatric patients.

METHODS

Consecutive cases of mandibular reconstruction with vascularized free fibula flaps in pediatric patients at Peking University School and Hospital of Stomatology between 1999 and 2019 were reviewed. Postoperative computed tomography (CT) data of all patients were collected at each postoperative follow-up point, and after the age of 18 years. The length and height of the grafted fibula and the length of the remaining mandible were evaluated by measuring the three-dimensional CT data using ProPlan CMF 3.0 software. Lower limb function was evaluated using the Enneking evaluation scale. Facial symmetry was self-evaluated and scored. Statistical analysis was performed on the data obtained.

RESULTS

Fourteen patients were included in this study. All flaps were successful. The CT measurement results showed growth in the length of the grafted fibula that reconstructed the mandibular ramus and the residual mandible ( P < 0.05). The height of the grafted fibula remained stable ( P > 0.05). Eight patients were followed up until they were older than 18 years, and the CT measurement results after 18 years showed an essentially symmetric mandible profile ( P > 0.05). All patients were satisfied with their postoperative facial symmetry. Enneking evaluation scores showed good recovery of lower limb functions.

CONCLUSIONS

The vascularized free fibula flap for mandibular reconstruction in pediatric patients is safe and reliable. It also provides good cosmetic and functional outcomes, as it demonstrated positive growth.

CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV.

摘要

背景

本研究旨在评估血管化游离腓骨瓣在儿童患者下颌骨重建中的长期效果。

方法

回顾北京大学口腔医学院 1999 年至 2019 年期间连续采用血管化游离腓骨瓣行下颌骨重建术的儿童患者病例。所有患者术后均定期行 CT 检查,在 18 岁以后每年进行 CT 随访。采用 ProPlan CMF 3.0 软件对三维 CT 数据进行测量,评估移植腓骨的长度和高度及剩余下颌骨的长度。采用 Enneking 评分评估下肢功能,患者对术后面部对称性进行自评和打分。对所得数据进行统计学分析。

结果

本研究共纳入 14 例患者,所有游离腓骨瓣均成活。CT 测量结果显示,重建下颌骨髁突和剩余下颌骨的移植腓骨长度有增长(P<0.05),腓骨高度保持稳定(P>0.05)。8 例患者随访至 18 岁以上,18 岁后 CT 测量结果显示下颌骨轮廓基本对称(P>0.05)。所有患者均对术后面部对称性满意。Enneking 评分显示下肢功能恢复良好。

结论

血管化游离腓骨瓣用于儿童患者下颌骨重建安全可靠,且能获得良好的美学和功能效果,腓骨有明显的生长。

临床问题/证据水平:治疗,IV。

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