School of Medicine, Rocky Vista University, Ivins, UT, USA.
Gastroenterology and Hepatology, University of Utah Health, Salt Lake City, UT, USA.
Endocr Metab Immune Disord Drug Targets. 2023;23(11):1355-1358. doi: 10.2174/1871530323666230411141412.
Pancreatic neuroendocrine neoplasms (PNETs) are rare but can be associated with significant morbidity and mortality. PNETs can be difficult to diagnose and have a propensity for metastasis before their diagnosis is established. To this end, many PNETs do not become apparent until late in their clinical course. Endoscopic ultrasound (EUS) has become the modality of choice for detecting these lesions due to its high tumor detection rate. Additionally, therapeutic techniques have arisen from EUS which allow for the treatment of PNETs. Overall, EUS has become a powerful diagnostic and therapeutic modality for addressing pancreatic lesions such as PNETs. In this perspective article, we provide an overview of the therapeutic potentials of EUS in the management of PNETs.
胰腺神经内分泌肿瘤(PNETs)较为罕见,但可导致严重的发病率和死亡率。PNETs 的诊断较为困难,在确诊前往往具有转移倾向。因此,许多 PNETs 直到其临床病程晚期才变得明显。由于其高肿瘤检出率,内镜超声(EUS)已成为检测这些病变的首选方式。此外,EUS 还产生了一些治疗技术,可用于 PNETs 的治疗。总体而言,EUS 已成为解决 PNET 等胰腺病变的一种强大的诊断和治疗方式。在本文中,我们概述了 EUS 在 PNETs 治疗中的治疗潜力。