与胃肠道间质瘤相关的非胰岛细胞瘤性低血糖症：病例报告及文献复习

Non-islet cell tumor hypoglycemia associated with Gastrointestinal Stromal Tumor: Case report and review of the literature.

作者信息

Kumar Vikash, Gala Dhir, Wonders Carson, Marowa Sabrin, Forlemu Arnold, Gayam Vijay, Reddy Madhavi

机构信息

Department of Internal Medicine, The Brooklyn Hospital Center, New York, USA.

School of Medicine, American University of the Caribbean, Cupecoy, Sint Maarten.

出版信息

Arch Clin Cases. 2023 Mar 27;10(1):50-54. doi: 10.22551/2023.38.1001.10240. eCollection 2023.

DOI:10.22551/2023.38.1001.10240

PMID:37056950

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10088052/

Abstract

Non-islet cell tumor hypoglycemia is an uncommon paraneoplastic phenomenon commonly associated with tumors of mesenchymal origin like gastrointestinal stromal tumors (GIST). It causes the release of insulin-like growth factor type II. GIST are frequently asymptomatic but can present with vague symptoms such as gastrointestinal bleeding, gastric pain, anorexia, nausea, and vomiting. We present an interesting case of A 62-year-old male with GIST tumor admitted for refractory hypoglycemia found to have non-islet cell tumor hypoglycemia which is a relatively uncommon cause of hypoglycemia.

摘要

非胰岛细胞瘤性低血糖症是一种罕见的副肿瘤现象，通常与间叶组织来源的肿瘤相关，如胃肠道间质瘤（GIST）。它会导致II型胰岛素样生长因子的释放。胃肠道间质瘤通常无症状，但可能出现诸如胃肠道出血、胃痛、厌食、恶心和呕吐等模糊症状。我们报告了一例有趣的病例，一名62岁男性因GIST肿瘤入院治疗难治性低血糖症，发现患有非胰岛细胞瘤性低血糖症，这是一种相对罕见的低血糖原因。