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表现为症状性低血糖的盆腔软组织胃肠道间质瘤：一例报告及非胰岛细胞瘤所致低血糖症当前文献的简要综述

Gastrointestinal stromal tumor of the pelvic soft tissue presenting with symptomatic hypoglycemia: A case report and brief review of current literature of non-islet cell tumor-induced hypoglycemia.

作者信息

Dean Kathleen, Hsieh Jessica, Morosky Christopher, Hoffman James

机构信息

Department of Obstetrics and Gynecology, University of Connecticut Integrated Residency Program, Farmington, CT, USA.

Department of Obstetrics and Gynecology, The Hospital of Central Connecticut, Farmington, CT, USA.

出版信息

Gynecol Oncol Case Rep. 2012 Apr 13;2(3):87-8. doi: 10.1016/j.gynor.2012.04.003. eCollection 2012.

DOI:10.1016/j.gynor.2012.04.003
PMID:24371628
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3861003/
Abstract

► Presentation of a rare case of pelvic gastrointestinal stromal tumor. ► Non-islet cell induced hypoglycemia causing severe hypoglycemia. ► The pathogenesis of non-islet cell induced hypoglycemia due to over-production of precursors of insulin-like growth factor-II. ► Complete resolution of hypoglycemia following resection of the tumor.

摘要

► 一例罕见的盆腔胃肠道间质瘤病例报告。

► 非胰岛细胞引起的低血糖导致严重低血糖。

► 胰岛素样生长因子-II前体过度产生导致非胰岛细胞性低血糖的发病机制。

► 肿瘤切除后低血糖完全缓解。

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本文引用的文献

1
Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: a randomised, double-blind, placebo-controlled trial.局部原发性胃肠间质瘤切除术后辅助使用甲磺酸伊马替尼：一项随机、双盲、安慰剂对照试验。
Lancet. 2009 Mar 28;373(9669):1097-104. doi: 10.1016/S0140-6736(09)60500-6. Epub 2009 Mar 18.
2
A gastrointestinal stromal tumor presenting as a pelvic mass: A case report.一例表现为盆腔肿块的胃肠道间质瘤：病例报告。
Oncol Rep. 2009 Apr;21(4):899-902. doi: 10.3892/or_00000301.
3
Insulin and insulin-like growth factor signalling in neoplasia.肿瘤形成中的胰岛素及胰岛素样生长因子信号传导
Nat Rev Cancer. 2008 Dec;8(12):915-28. doi: 10.1038/nrc2536.
4
Non-islet cell tumour-induced hypoglycaemia: a review of the literature including two new cases.非胰岛细胞瘤所致低血糖症：文献综述并附两例新病例
Endocr Relat Cancer. 2007 Dec;14(4):979-93. doi: 10.1677/ERC-07-0161.
5
Severe hypoglycemia caused by paraneoplastic production of IGF-II in patients with advanced gastrointestinal stromal tumors: a report of two cases.晚期胃肠道间质瘤患者副肿瘤性产生胰岛素样生长因子-II导致严重低血糖症：两例报告
J Clin Oncol. 2005 Sep 20;23(27):6809-11. doi: 10.1200/JCO.2005.02.4828.
6
The effectiveness of different treatment options for non-islet cell tumour hypoglycaemia.非胰岛细胞瘤低血糖症不同治疗方案的有效性
Clin Endocrinol (Oxf). 2004 Apr;60(4):457-60. doi: 10.1111/j.1365-2265.2004.01989.x.
7
GI stromal tumors.胃肠道间质瘤
Gastrointest Endosc. 2003 Jul;58(1):80-8. doi: 10.1067/mge.2003.317.
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Pol J Pathol. 2003;54(1):3-24.