睡眠呼吸障碍患儿的神经认知能力。病例对照研究的系统评价和荟萃分析。

Neurocognitive abilities in children affected by sleep breathing disorders. A systematic review and meta-analysis of case control-studies.

作者信息

Fantozzi D, Doldo T, Luzi C, Grandini S, Marruganti C

机构信息

Unit of Orthodontics, Department of Medical Biotechnologies, University of Siena, Siena, Italy.

Unit of Endodontology, Restorative dentistry and Periodontology, Department of Medical Biotechnologies, University of Siena, Siena, Italy.

出版信息

Eur J Paediatr Dent. 2023 Mar 1:1. doi: 10.23804/ejpd.2023.1818.

DOI:10.23804/ejpd.2023.1818

PMID:37057342

Abstract

AIM

Different experimental approaches have demonstrated that children with sleep breathing disorders (SBD) exhibit neurocognitive and behavioural impairment. The present systematic review and meta-analysis aims to quantify neurocognitive deficit disorders in mouth breathing paediatric patients by summarising relevant case-controls studies. Neurocognitive assessment was undertaken with WISC.

METHODS

A search strategy was developed on electronic databases including Medline (Pubmed), Scopus, Scileo; Cochrane library from 2000 to June 2022 for published studies analysing neurocognitive skills in children with SBD compared to healthy control groups. The review was performed according to the PRISMA protocol and articles were selected according to the established inclusion and exclusion criteria. The Weighted Mean Differences (95% Confidence Intervals) were calculated between results obtained in WISC tests in SBD patients and healthy subjects.

CONCLUSION

Our results confirmed that SBD affected children performed worse than healthy children in terms of quite all the cognitive domains investigated.

摘要

目的

不同的实验方法表明，患有睡眠呼吸障碍（SBD）的儿童存在神经认知和行为障碍。本系统评价和荟萃分析旨在通过总结相关病例对照研究，量化口呼吸儿科患者的神经认知缺陷障碍。使用韦氏儿童智力量表（WISC）进行神经认知评估。

方法

制定了一项检索策略，在包括Medline（PubMed）、Scopus、Scileo在内的电子数据库以及Cochrane图书馆中检索2000年至2022年6月发表的研究，这些研究分析了SBD儿童与健康对照组相比的神经认知技能。根据PRISMA协议进行综述，并根据既定的纳入和排除标准选择文章。计算SBD患者和健康受试者在WISC测试中获得的结果之间的加权平均差异（95%置信区间）。