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子宫内淋巴间质肌病伴卵巢转移及阴道复发

Endolymphatic stromal myosis of the uterus with metastasis to ovary and recurrence in vagina.

作者信息

Yu T J, Iwasaki I, Horie H, Tamaru J, Takahashi A

出版信息

Acta Pathol Jpn. 1986 Feb;36(2):301-8. doi: 10.1111/j.1440-1827.1986.tb01483.x.

DOI:10.1111/j.1440-1827.1986.tb01483.x
PMID:3705963
Abstract

A 24-year-old woman underwent a supracervical hysterectomy with findings of an endolymphatic stromal myosis (ESM) with vascular invasion as a submucosal tumor of the uterine fundus. Four years later, metastasis of ESM in the right ovary was found after salpingo-oophoréctomy. Parametrial masses and a tumor infiltrated cervical stump revealed the same structure of ESM after operation. Though subtotal excision of the pelvic and vaginal recurrences nine years after the first operation for ESM and in spite of oral administration of danazol and duphaston (hydrogesterone), a recurrent vaginal tumor developed after the fourth operation and local application of chemotherapy with 5-fluorouracil was given. At present, the patient's condition is stable without distant metastasis.

摘要

一名24岁女性接受了次全子宫切除术,术中发现子宫底黏膜下肿瘤为伴有血管侵犯的淋巴管内间质肌病(ESM)。四年后,输卵管卵巢切除术后发现右侧卵巢有ESM转移。术后,子宫旁肿块和浸润宫颈残端的肿瘤显示出与ESM相同的结构。尽管在首次手术治疗ESM九年后对盆腔和阴道复发灶进行了次全切除,且口服了达那唑和多羟孕酮,但在第四次手术后仍出现了复发性阴道肿瘤,并给予了5-氟尿嘧啶局部化疗。目前,患者病情稳定,无远处转移。

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