Germain G, Lopes P, Cabrol D, Barbe M P, Huneau D, Le Houezec R, Sureau C
Acta Physiol Hung. 1986;67(1):95-115.
The use of a combination of manometric and electromyographic methods provided a reliable technique for evaluating variations in uterine activity in conscious macaque monkeys and women. The technique was particularly useful for obtaining data on the influence of steroid hormones. During the spontaneous menstrual cycle of the macaque, uterine motility, after being weak and poorly synchronized during the follicular phase, became still weaker with impaired synchronization during the luteal phase and then much stronger and well-synchronized at the time of menstruation. There was no evidence in vivo of any relationship between the existence of gap junctions in the myometrium of non-pregnant animals and the various patterns of uterine motility. During the last third of pregnancy in macaques, the initiation of electrical activity in various uterine areas was always synchronous with and related to mechanical contraction. The same results were obtained in preparturient women. Thus, improved uterine coordination does not appear to be the mechanism by which the uterine contractile strength increases to expulse the foetus at the end of pregnancy. Apart from the particular situation of non-pregnant animals under progestative influence, in which activity was constantly non-propagated, we could not find any evidence of a general pattern which would indicate only one site for the initiation of activity and its extension to the whole uterus.
压力测量法和肌电图方法相结合，为评估清醒猕猴和女性子宫活动的变化提供了一种可靠的技术。该技术对于获取有关甾体激素影响的数据特别有用。在猕猴的自发月经周期中，子宫运动在卵泡期较弱且同步性差，在黄体期变得更弱且同步性受损，然后在月经时变得更强且同步性良好。在非妊娠动物子宫肌层中缝隙连接的存在与子宫运动的各种模式之间，在体内没有任何关系的证据。在猕猴妊娠的最后三分之一期间，子宫各个区域电活动的起始总是与机械收缩同步并相关。在临产前的女性中也得到了相同的结果。因此，子宫协调性的改善似乎不是妊娠末期子宫收缩力增加以排出胎儿的机制。除了在孕激素影响下非妊娠动物的特殊情况（其活动持续不传播）外，我们找不到任何表明仅一个活动起始部位并将其扩展到整个子宫的一般模式的证据。
