Department of Medicine, University of California Irvine Medical Center, Orange, CA.
Department of Medicine, University of California Irvine Medical Center, Orange, CA; Chao Family Comprehensive Cancer Center, University of California Irvine, Orange, CA.
Clin Lymphoma Myeloma Leuk. 2023 Jun;23(6):401-409. doi: 10.1016/j.clml.2023.03.003. Epub 2023 Mar 17.
The term cutaneous T-cell lymphoma (CTCL) is a general term for T-cell lymphomas that are found primarily in skin. The most common CTCL entities, mycosis fungoides and Sezary syndrome are incurable diseases with a plethora of conventional treatment options. In the past treatment options have been selected primarily according to stage. Given newer targeted therapies with varied response in different body compartments, we suggest a compartment-guided algorithm that may enhance response rates directing the selection of the most efficacious treatment options.
皮肤 T 细胞淋巴瘤（CTCL）是一个广义术语，用于指代主要发生在皮肤的 T 细胞淋巴瘤。蕈样真菌病和 Sezary 综合征是最常见的 CTCL 实体，它们是无法治愈的疾病，有大量的常规治疗选择。过去，治疗选择主要根据分期进行。鉴于不同身体部位对不同靶向治疗的反应不同，我们建议采用基于部位的算法，这可能会提高反应率，指导选择最有效的治疗方法。
