Granö Niklas, Lintula Sakari, Therman Sebastian, Marttunen Mauri, Lång Ulla, Ranta Klaus
Faculty of Medicine, Department of Psychiatry, Psychiatry, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
Department of Psychiatry, Helsinki University Hospital, Helsinki, Finland.
Early Interv Psychiatry. 2023 Dec;17(12):1199-1206. doi: 10.1111/eip.13417. Epub 2023 Apr 16.
Psychosis-Like Experiences (PLEs) and depressive symptoms are correlated in clinical adolescent populations. However, symptom-level associations between the two phenomena are not clear.
We analysed factor structures of a PLE instrument, the Prodromal Questionnaire-Brief (PQ-B), based on dimensions of positive symptoms of schizophrenia, and a depression measurement instrument, the Beck Depression Inventory (BDI-21A) and performed a network analysis of item-level associations between the two measures. The sample consisted of 417 adolescents (range 13-18 years of age, mean 14.9 years, 72.4% females) entering secondary psychiatric services at Helsinki metropolitan area, Finland.
Confirmatory factor analysis resulted in adequately fitting 2-factor solution, one for PQ-B and one for BDI-21, with a strong correlation coefficient of 0.605 between the two factors. In the network analysis, PQ-B and BDI-21 both formed their own clusters, and two significant pathways were estimated between PQ-B and BDI-21 clusters: 1. the association between paranoid thinking and distorted body image, and 2. the association between somatic preoccupation and worry about problems of one's mind.
Even though on a general, factor level, PLEs and depressive symptoms were strongly correlated, unique associations between symptoms of the two constructs were sparse. These findings should be considered in the psychiatric assessment and in the care of adolescents.
在临床青少年群体中,类精神病体验(PLEs)与抑郁症状相关。然而,这两种现象之间症状层面的关联尚不清楚。
我们基于精神分裂症的阳性症状维度,分析了一种PLE工具即简易前驱症状问卷(PQ - B)的因子结构,以及一种抑郁测量工具即贝克抑郁量表(BDI - 21A),并对这两种测量工具之间的项目层面关联进行了网络分析。样本包括417名青少年(年龄范围13 - 18岁,平均14.9岁,72.4%为女性),他们在芬兰赫尔辛基大都市区接受二级精神科服务。
验证性因子分析得出了拟合良好的双因子解决方案,一个用于PQ - B,一个用于BDI - 21,两个因子之间的相关系数为0.605。在网络分析中,PQ - B和BDI - 21都形成了各自的聚类,并且在PQ - B和BDI - 21聚类之间估计有两条显著路径:1. 偏执思维与身体形象扭曲之间的关联,以及2. 躯体先占观念与对自身心理问题的担忧之间的关联。
尽管总体上在因子水平上,PLEs与抑郁症状密切相关,但这两种结构症状之间的独特关联很少。在青少年的精神病学评估和护理中应考虑这些发现。