Iyer S K, Chandrasekhara K L, Sutton A
Am J Med. 1986 May;80(5):849-52. doi: 10.1016/0002-9343(86)90627-3.
Six cases of diffuse muscular hypertrophy of the esophagus are reported. The clinical diagnosis is often missed and may be confused with achalasia. Some clinical features that help distinguish this disease are a sensation of "grasping" any tube or instrument introduced into the esophagus, marked sustained elevation in the baseline pressure in the body of the esophagus over a longer segment, and poor response to forced pneumatic dilatation (in those cases in which achalasia is suspected). An interesting association was the relationship with diabetes mellitus in four of the six cases described.
报告了6例食管弥漫性肌肉肥大病例。临床诊断常常被漏诊，且可能与贲门失弛缓症相混淆。有助于鉴别该病的一些临床特征包括：对插入食管的任何导管或器械有“紧握”感、食管体部较长节段的基线压力显著持续升高、以及对强力气囊扩张反应不佳（在怀疑为贲门失弛缓症的病例中）。一个有趣的关联是，在所描述的6例病例中有4例与糖尿病相关。
