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韩国实体器官移植机构病例数量对患者预后的影响及对医疗政策的启示

Impact of institutional case volume of solid organ transplantation on patient outcomes and implications for healthcare policy in Korea.

作者信息

Kang Christine, Ryu Ho Geol

机构信息

Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.

出版信息

Korean J Transplant. 2023 Mar 31;37(1):1-10. doi: 10.4285/kjt.23.0010.

Abstract

Solid organ transplantation is distinguished from other high-risk surgical procedures by the fact that it utilizes an extremely limited and precious resource and requires a multidisciplinary team approach. For several decades, institutional experience, as quantified by center volume, has been shown to be strongly associated with patient outcomes and graft survival after solid organ transplantation. The United States has implemented a minimum case volume requirement and performance standards for accreditation as a validated transplantation center. Solid organ transplantation in Europe is also governed by the European Union, which monitors patient outcomes and organ allocation. The number of solid organ transplantation cases in Korea is increasing, with patient outcomes comparable to international standards. However, Korea has outdated regulations regarding hospital facilities, and performance indicators including patient outcomes after transplantation are not monitored. Therefore, centers perform solid organ transplantation with no meaningful oversight. In this review, data regarding the impact of institutional case volume of kidney, liver, lung, and heart transplantation are summarized, followed by a description of current transplantation center regulations in the United States and Europe. The basis for the necessity of adequate transplantation center regulations in Korea is presented.

摘要

实体器官移植与其他高风险外科手术的不同之处在于,它使用的是极其有限且珍贵的资源,并且需要多学科团队协作。几十年来,机构经验(以中心手术量来衡量)已被证明与实体器官移植后的患者预后和移植物存活密切相关。美国已实施了作为经过验证的移植中心的最低病例数量要求和认证绩效标准。欧洲的实体器官移植也受欧盟监管,欧盟会监测患者预后和器官分配情况。韩国的实体器官移植病例数量在增加,患者预后与国际标准相当。然而,韩国关于医院设施的法规已经过时,且包括移植后患者预后在内的绩效指标并未得到监测。因此,各中心在没有有效监督的情况下开展实体器官移植。在本综述中,总结了有关肾脏、肝脏、肺和心脏移植机构病例数量影响的数据,随后描述了美国和欧洲目前的移植中心法规。阐述了韩国制定适当移植中心法规的必要性依据。

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