Patil Sanath, Siddique Faizaan, Rahimov Daler, Rajagopal Keshava, Entwistle John W, Bodzin Adam, Tchantchaleishvili Vakhtang
Department of Cardiac Surgery, Thomas Jefferson University, 1025 Walnut St, Suite 607, Philadelphia, PA, 19107, USA.
Division of Transplant Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
Gen Thorac Cardiovasc Surg. 2025 Jul 10. doi: 10.1007/s11748-025-02178-3.
We sought to understand how centers transplanting liver only (L0), centers transplanting heart and liver (LH), and centers transplanting liver, heart, and lung (LHL) differ regarding volume, waitlist and post-transplant outcomes.
Data were collected from the Scientific Registry of Transplant Recipients (SRTR) in July 2023. SRTR star ratings were categorized into five tiers, with one being the lowest tier and five the highest tier.
Median liver transplant volumes were 35 [IQR: 14-51] for L0 centers, 45 [10-75] for LH centers, and 101 [69-131] for LHL centers (p < 0.001). Liver waitlist survival (p = 0.13), waitlist duration (p = 0.31) and 1-year survival ratings (p = 0.32) were comparable across all 3 categories. Annual transplant volume was associated with a higher SRTR waitlist duration rating (p < 0.001) but not with 1-year post-transplant survival (p = 0.51).
The presence of a heart transplant and lung transplant programs in liver transplant centers is associated with higher liver transplant volumes, translating to higher waitlist duration tier ratings for liver recipients, but not to improved 1-year post-transplant survival.
我们试图了解仅进行肝脏移植的中心(L0)、进行心脏和肝脏移植的中心(LH)以及进行肝脏、心脏和肺移植的中心(LHL)在移植量、等待名单和移植后结果方面有何不同。
2023年7月从移植受者科学注册系统(SRTR)收集数据。SRTR星级分为五个等级,一级为最低等级,五级为最高等级。
L0中心肝脏移植量中位数为35[四分位间距:14 - 51],LH中心为45[10 - 75],LHL中心为101[69 - 131](p < 0.001)。所有三个类别在肝脏等待名单生存率(p = 0.13)、等待名单持续时间(p = 0.31)和1年生存率评级(p = 0.32)方面具有可比性。年度移植量与SRTR等待名单持续时间评级较高相关(p < 0.001),但与移植后1年生存率无关(p = 0.51)。
肝脏移植中心存在心脏移植和肺移植项目与更高的肝脏移植量相关,这意味着肝脏受者的等待名单持续时间评级更高,但移植后1年生存率并未提高。