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经皮冠状动脉介入治疗对QT离散度的影响及其相关性:一项系统评价

The Effect of Percutaneous Coronary Intervention on QT Dispersion and the Association Between Them: A Systematic Review.

作者信息

Dahrab Mahdi, Gaddipati Sai Pranathi, Patel Keval B, Patel Tirath, Gaddam Ashwith R, Jain Manisha, Gudi Thulasi Ram, Meenashi Sundaram Dakshin, Mahfooz Kamran, Vasavada Advait M

机构信息

Internal Medicine, McMaster University, Hamilton, CAN.

Internal Medicine, Mallareddy Medical College for Women, Hyderabad, IND.

出版信息

Cureus. 2023 Mar 16;15(3):e36226. doi: 10.7759/cureus.36226. eCollection 2023 Mar.

Abstract

Electrocardiography (ECG) parameters are significant in the prognosis of ischemia and other cardiovascular conditions. Reperfusion or revascularization techniques are essential in reestablishing blood flow to ischemic tissues. This study aims to demonstrate the association between percutaneous coronary intervention (PCI), a revascularization technique, and the electrocardiography (ECG) parameter, QT dispersion (QTd). We conducted a systematic review of the association between PCI and QTd through a literature search in three electronic databases, ScienceDirect, PubMed, and Google Scholar, for empirical studies published in English. Review Manager (RevMan) 5.4 (Cochrane Collaboration, Oxford, England) was used for statistical analysis. Of 3,626 studies, 12 articles met the inclusion criteria, enrolling a total of 1,239 patients. After a successful PCI procedure, QTd and corrected QT (QTc) tremendously reduced at various time intervals with statistical significance in most of the studies. There was a clear association between ECG parameters QTd, QTc, and corrected QT dispersion (QTcd), and PCI, in that there is a considerable reduction in these ECG parameters after PCI treatment.

摘要

心电图(ECG)参数在缺血及其他心血管疾病的预后中具有重要意义。再灌注或血管重建技术对于恢复缺血组织的血流至关重要。本研究旨在证明血管重建技术经皮冠状动脉介入治疗(PCI)与心电图(ECG)参数QT离散度(QTd)之间的关联。我们通过在三个电子数据库ScienceDirect、PubMed和谷歌学术搜索英文发表的实证研究,对PCI与QTd之间的关联进行了系统评价。使用Review Manager(RevMan)5.4(Cochrane协作网,英国牛津)进行统计分析。在3626项研究中,12篇文章符合纳入标准,共纳入1239例患者。在大多数研究中,成功进行PCI术后,QTd和校正QT(QTc)在不同时间间隔内显著降低。心电图参数QTd、QTc和校正QT离散度(QTcd)与PCI之间存在明显关联,即PCI治疗后这些心电图参数有显著降低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/607c/10103800/2921fa24fb01/cureus-0015-00000036226-i01.jpg

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