Wark K J, Sebel P S, Verghese C, Maynard D E, Evans S J
Anaesthesia. 1986 Apr;41(4):390-4. doi: 10.1111/j.1365-2044.1986.tb13224.x.
Recordings of cerebral electrical activity were obtained using the cerebral function analysing monitor from eight unpremedicated patients anaesthetised with increasing concentrations of halothane in oxygen. The amplitude of the processed EEG increased at one and decreased at two minimal alveolar concentrations. The frequency distribution of the weighted EEG signal showed a linear increase of delta activity with a corresponding decrease in beta activity with increasing concentrations of halothane.