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乳腺假血管瘤样间质增生:临床评估。

Pseudoangiomatous stromal hyperplasia of the breast: Clinical evaluation.

机构信息

Department of Surgical Oncology, Faculty of Medicine, Mersin University, Mersin, Turkey.

出版信息

Breast Dis. 2023;42(1):115-119. doi: 10.3233/BD-220070.

Abstract

BACKGROUND

Pseudoangiomatous stromal hyperplasia is a rare benign breast stromal proliferative lesion of the breast. Clinical presentation ranges from rapidly growing mass to incidental identification in routine screening. This difference in manifestation and its rarity makes it difficult to be a standard treatment protocol. Therefore, we aimed to share our clinical experience in Pseudoangiomatous stromal hyperplasia.

METHODS

The files of patients who underwent core biopsy or surgical excision due to a breast mass and resulted in pseudoangiomatous stromal hyperplasia between January 2013 and December 2021 were included in the study.

RESULTS

17 patients with a median age of 37 (22-68) were found Pseudoangiomatous stromal hyperplasia confirmed by surgical excision or core biopsy. Chosen treatment option was observation in 8 patients (47.1%), while surgical excision was used in 9 (52.9%) patients. The mean follow-up period was 55.24 ± 26.72 (13-102) months. None of the patients observed the Malignant transformation during the follow-up period.

CONCLUSION

For Pseudoangiomatous Stromal Hyperplasia of the breast, surgical excision with clean margins or close follow-up after diagnosis confirmation by tissue biopsy is sufficient. Pseudoangiomatous Stromal Hyperplasia is not a risk factor for developing breast cancer.

摘要

背景

假血管瘤样间质增生是一种罕见的乳腺良性间质增生性病变。临床表现从快速生长的肿块到常规筛查中的偶然发现不等。这种表现上的差异及其罕见性使得制定标准治疗方案变得困难。因此,我们旨在分享我们在假血管瘤样间质增生方面的临床经验。

方法

本研究纳入了 2013 年 1 月至 2021 年 12 月期间因乳腺肿块而行核心活检或手术切除并确诊为假血管瘤样间质增生的患者的病历。

结果

发现 17 名经手术切除或核心活检证实为假血管瘤样间质增生的患者,年龄中位数为 37 岁(22-68 岁)。8 名患者(47.1%)选择观察治疗,9 名患者(52.9%)采用手术切除。平均随访时间为 55.24±26.72 个月(13-102 个月)。在随访期间,没有患者观察到恶性转化。

结论

对于乳腺假血管瘤样间质增生,手术切除切缘干净或组织活检确诊后密切随访就足够了。假血管瘤样间质增生不是乳腺癌发生的危险因素。

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