Department of Dermatology & STD, Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi, India.
Australas J Dermatol. 2023 Aug;64(3):e299-e301. doi: 10.1111/ajd.14059. Epub 2023 Apr 17.
In a rare case of concurrent verrucous epidermal naevi (VEN) with psoriasis, previous treatments with oral methotrexate and acitretin showed minimal improvement. However, treatment with oral apremilast resulted in complete resolution of psoriasis and significant improvement in VEN lesions after 1 month. This is the first documented case of successful VEN treatment with apremilast, highlighting its potential efficacy in treating verrucous epidermal naevus. Further studies are needed to validate its effectiveness.
在一例罕见的并发疣状表皮痣(VEN)和银屑病病例中,先前口服甲氨蝶呤和阿维 A 的治疗仅显示出最小的改善。然而,口服阿普米司特治疗 1 个月后,银屑病完全缓解,VEN 病变显著改善。这是首例成功用阿普米司特治疗 VEN 的病例,突出了其在治疗疣状表皮痣方面的潜在疗效。需要进一步的研究来验证其有效性。