[Clinical forms of skin manifestations in allergy to perfume].

Perfumes are increasingly used in an ever wider variety of fields, including perfumes proper, cosmetic products, hygienic products, drugs, detergents and other household products, plastics, industrial greases, oils and solvents, foods, etc. Their composition is usually complex; it involves numerous natural and synthetic sweet-smelling constituents, more than 5,000 of which are known (13). Perfumes may produce toxic and, more often, allergic respiratory disorders (asthma), as well as neurological (10) and cutaneous disorders. They are the most common cause of skin allergy to cosmetic products (1, 11) and one of the most important causes of skin allergy to topical drugs or even to syrups which may reactivate contact dermatitis (24). People engaged in the manufacturing of these products may become sensitized to perfumes.