Suhartono Suhartono, Mahdani Wilda, Muzayanna Nyak Naiza
Department of Biology, Faculty of Mathematics and Natural Science, Universitas Syiah Kuala, Banda Aceh, Indonesia.
Department of Microbiology, Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia.
Iran J Microbiol. 2023 Feb;15(1):38-44. doi: 10.18502/ijm.v15i1.11916.
is one of the multiple intrinsic resistant bacteria causing opportunistic infections. The study aimed to determine the distribution of isolates based on types of clinical specimen, hospital wards, and the patient's gender-age and to evaluate their antibiotic susceptibility.
This study involved isolating, identifying, and testing antibiotic susceptibility of isolates recovered from clinical specimens of Dr. Zainoel Abidin general hospital (RSUDZA) Banda Aceh Indonesia during March 2019-March 2022.
In total, there were 3,622 Gram-negative bacterial isolates of 10,192 clinical specimens obtained during the study period and was positively detected in 127 isolates (1.24%). Most of the 127 isolates of were found in blood and sterile body fluid samples (55.11%) followed by urine and pus samples accounting for 23.62% and 13.37%, respectively. The internal medicine wards had the highest number of detected isolates at 28.3%. infections were more common in men (59.05%) and people over 45 years old (41.73%). The bacteria were highly sensitive to the antibiotic ceftazidime (92.7%).
Culture examination of clinical specimens is not required for confirmed infections, despite being essential for appropriate antibiotic treatment. Implementing surveillance programs and judicious use of antibiotics can prevent bacterial transmission.
是引起机会性感染的多种固有耐药菌之一。本研究旨在根据临床标本类型、医院科室以及患者的性别年龄来确定分离株的分布情况,并评估它们的抗生素敏感性。
本研究涉及对2019年3月至2022年3月期间从印度尼西亚班达亚齐宰诺埃尔·阿比丁综合医院(RSUDZA)的临床标本中分离出的分离株进行分离、鉴定和抗生素敏感性测试。
在研究期间获得的10192份临床标本中,共有3622株革兰氏阴性菌分离株,其中127株(1.24%)被检测为阳性。127株分离株中,大多数存在于血液和无菌体液样本中(55.11%),其次是尿液和脓液样本,分别占23.62%和13.37%。内科病房检测到的分离株数量最多,为28.3%。感染在男性(59.05%)和45岁以上人群(41.73%)中更为常见。该细菌对头孢他啶抗生素高度敏感(92.7%)。
对于确诊感染,临床标本的培养检查并非必需,尽管它对于适当的抗生素治疗至关重要。实施监测计划和合理使用抗生素可以预防细菌传播。