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全胃切除术后影响胃恶性肿瘤患者5年生存率的因素。

Factors influencing 5-year survival in gastric malignancies after total gastrectomy.

作者信息

Saario I, Schröder T, Tolppanen E M, Lempinen M

出版信息

Ann Chir Gynaecol. 1986;75(1):23-7.

PMID:3707023
Abstract

One hundred consecutive patients were analysed who had been treated with total gastrectomy in the Second Department of Surgery, Helsinki University Central Hospital, for malignancies of the stomach from 1977 to 1982. Hospital mortality was 8%. The 5-year survival rate in this selected group of patients was 43% and 34% for patients with gastric cancer. Patients with metastases died within 42 months, more than half of them within one year. However, palliative total gastrectomy is recommended in proximally located obstructing tumours. Radical operations on patients with tumour growth to adjacent tissue and organs had no effect on the 5-year survival rates compared to those on patients with metastases. Surgical removal of the primary tumour is recommended in these cases as well. Patients without lymph node metastases had a survival rate of 67% but the prognosis was even better in cases with intact serosa (96%).

摘要

对1977年至1982年间在赫尔辛基大学中心医院第二外科接受全胃切除术治疗胃癌的100例连续患者进行了分析。医院死亡率为8%。在这一选定患者组中,5年生存率为43%,胃癌患者为34%。有转移的患者在42个月内死亡,其中一半以上在一年内死亡。然而,对于近端梗阻性肿瘤,建议行姑息性全胃切除术。与有转移的患者相比,对肿瘤侵犯相邻组织和器官的患者进行根治性手术对5年生存率没有影响。在这些情况下也建议手术切除原发肿瘤。无淋巴结转移的患者生存率为67%,但浆膜完整的患者预后更好(96%)。

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